生物制剂治疗类风湿关节炎经验与共识

Experience and consensus on biological agents for treatment of rheumatoid arthritis

生物制剂尤其是肿瘤坏死因子拮抗剂治疗可以有效改善类风湿关节炎患者的关节肿痛、晨僵等症状和体征,减缓或阻止关节骨质破坏的发生和发展,提高患者的功能状态和生活质量。经过多年广泛的应用,在很多方面已经积累了经验并达成了共识,这些可为中国医生更恰当地使用生物制剂提供帮助。

Biological agents, particularly tumor necrosis factor antagonists, have been the major advances in the treatment of rheumatoid arthritis. This could have been related to that fact that tumor necrosis factor antagonists may relieve the symptoms and signs including arthritis and morning stiffness, interrupt progression of bone damage and improve physical function and quality of life. The extensive application has enabled accumulation of mounting experiences and consensus in the treatment of rheumatoid arthritis. This may be worthwhile for Chinese clinicians to apply biological agents in an appropriate manner.