海黍子中甾醇类化合物的初步研究

Research of steroids from Sagassum muticum

从中国青岛海域采集的海洋褐藻海黍子(Sagassum muticum),经提取和纯化分离后,得到3个甾醇类化合物,经1 H-NMR、13C-NMR和MS等现代光谱手段鉴定,它们的结构分别为:岩藻甾醇(1)、马尾藻甾醇(2)和较为少见的24-乙基-2a-氧杂-2-氧-5α-羟基-3,4-二失碳-24(28)-胆甾烯(3),这是首次报道的从海黍子马尾藻中分离得到A环降二碳的甾醇类化合物.

Three steroids are isolated from the marine brown alga Sargassum muticum collected from the coast of Qingdao,Shandong Province,China.The chemical structures are identified by 1 HNMR,13 CNMR and MS as fucosterol（1）,saringosterol（2） and 24-ethyl-2a-oxa-5α-hydroxy-3,4-dinoreholestane（3）.This is the first report of A-binor steroid from natural sources of Sargassum muticum.