肝实性占位超声回声特性的病理基础

The histopathological basis of the characteristics of ultrasonic echo of liver solid mass

目的 了解决定肝实性占位病变超声回声特性的病理组织学基础。方法 12 0例患者的 3 7个高回声结节、91个低回声结节在超声引导下接受穿刺组织活检 ,并进行病理组织学分析。结果 12 8个结节中包含了各种良、恶性病变。高回声的共同组织学特点为 :含有非液化性坏死区、脂肪空泡、透明细胞、血窦或窦周隙扩张 ,上述结构的最小径 >0 .0 3mm且大片融合形成直径 >0 .40mm的集落簇。低回声病灶细胞排列致密无上述结构。结论 病灶内所含有的脂肪空泡、窦周隙的直径是构成回声特性的组织病理基础。

Objective To evaluate the histopathological basis which determines the sonograms echo characteristic of liver solid masses. Methods One hundred and twenty eight liver solid masses in 120 patients were examined by ultrasonography .The lesion sonograms were classified as hyperechoic or hypoechoic on the basic of the difference in echogenicity between the mass and the surrounding liver parenchyma,and then, the specimens of lesiones were taken by US guided liver biopsy and the histopathological structure were analyzed.Results Ninty seven malignant lesions and 31 benign lesions were included in the 128 masses,which included HCC, metastases,hemangioma,and hyperplasia.The hyperechoic lesions exhibited following histopathological characteristics : extensive nonliquetive necrosis ,fatty bubble ,transparent cells, sinusoidal dilation or blood sinusoidal and the diameter of these structure was larger than 0.03 mm and mass into the cluster of which the diameter was larger than 0.40 mm. The hypoechoic lesions had tight cells structure.Conclusion The diameter of fatty bubble, sinusoid and blood sinus was the histopathological basis of the sonograms characteristic of liver solid masses.