摘要
目的探讨两种不同厂家坦索罗辛治疗良性前列腺增生的疗效及成本-效果。方法将238例良性前列腺增生患者随机分为治疗组和对照组,每组119例。治疗组服用必坦(盐酸坦索罗辛缓释胶囊),对照组服用哈乐(盐酸坦索罗辛缓释胶囊),均用药4周。观察两组的国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、综合疗效及成本-效果比。结果治疗4周后,治疗组和对照组综合疗效总有效率分别为87.39%和86.55%,两组之间差异无统计学意义(P>0.05);国际前列腺症状评分(IPSS)、最大尿流率(Qmax)均有明显改善,两组之间差异无统计学意义(P>0.05);两组的成本-效果比,治疗组优于对照组。结论必坦(盐酸坦索罗辛缓释胶囊)治疗良性前列腺增生疗效显著,成本相对较低。
Objective To explore the effect and the cost- effectiveness of tamsulosin produced by 2 different manufactories for treating benign prostatic hyperplasia(BPH). Methods Two hundred and thirty-eight cases of BPH were randomly divided into two groups, 119 cases in each group. The treatment group was treated with oral homemade Tamsulosin Hydrochloride Sustained Release Capsule for 4 weeks, while the control group was treated with oral imported Homemade Tamsulosin Hydrochloride Sustained Release Capsule for 4 weeks. The International Prostate Symptoms Score (IPSS), maximum urine rate of flow (Qmax), comprehensive effects and cost- effec- tiveness were observed between two groups. Results After 4- week treatment, the total effective rate were 87.39% in the treatment group and 86.55% in the control group respectively, without statistical difference between the two groups(P〉0.05).The IPSS scores and Qmax were improved greatly, there was no statistical difference between the two groups(P 〉 0.05). The ratio of cost-effectiveness in the treatment group was superior to that in the control group. Conclusion Homemade Tamsulosin Hydrochloride Sustained Release Capsule has significant effects in treating BPH with lower relative cost.
出处
《中国药业》
CAS
2012年第17期40-41,共2页
China Pharmaceuticals
关键词
盐酸坦索罗辛缓释胶囊
良性前列腺增生
成本-效果
Tamsulosin Hydroehloride Sustained Release Capsule
benign prostatic hyperplasia (BPH)
cost-effectiveness