匙羹藤根部乙酸乙酯部分的化学成分研究

Research on Chemical Compositions of Acetoacetate in the Root of Gymnema Sylvestre

目的:对匙羹藤根乙酸乙酯部分的化学成分进行研究。方法:应用各种现代色谱手段对其化学成分进行分离纯化,利用理化性质结合光谱数据鉴定化合物结构。结果:分离鉴定了5个化合物,分别为正二十烷(Ⅰ)、豆甾醇(Ⅱ)、β-谷甾醇(Ⅲ)、正二十二烷酸(Ⅳ)、牛弥菜醇A(Ⅴ)。结论:该方法能首次从该植物中分离得到化合物Ⅰ和Ⅳ。

Objective： To study the Chemical compositions of acetoacetate in the Root of Gymnema sylvestre. Methods： The compunds were isolated by many kinds of chromatography methods and identified on the basis of physico-chemical char- acters and spectroscopic analysis. Results： Five compounds were obtained from the ethyl acetate extract of Gymnema sylvestre （Retz.） Schuh root, and their structures were identified as icosane （I）, Stigmasterol （I I）, -sitosterol （Ⅲ）, docosanoic acid （IV） and conduritol A （V）. Conclusion： Compounds I and 1V are isolated from this plant for the first time.