盘龙七化学成分研究(Ⅱ)

Chemical constituents from rhizomes of Bergenia scopulosa (Ⅱ)

目的研究盘龙七Bergenia scopulosa的化学成分。方法采用多种色谱技术对其进行分离纯化,根据理化性质和光谱数据鉴定化合物结构。结果从盘龙七甲醇提取物中分离得到16个化合物,分别鉴定为岩白菜素(1)、(+)-儿茶素(2)、熊果苷(3)、6-O-没食子酰基熊果苷(4)、(+)-儿茶素-7-O-β-D-吡喃葡萄糖苷(5)、苯丙氨酸(6)、琥珀酸(7)、原儿茶酸(8)、没食子酸(9)、没食子酸甲酯(10)、槲皮素(11)、金丝桃苷(12)、芦丁(13)、阿福豆苷(14)、大黄酚-8-O-β-D-吡喃葡萄糖苷(15)、11-O-没食子酰岩白菜素(16)。结论化合物5～16为首次从该植物中分离得到。

Objective To study the chemical constituents from the rhizomes of Bergenia scopulosa. Methods The constituents were isolated and purified by column chromatography. Their structures were identified on the basis of physiochemical properties and spectral analyses. Results Sixteen compounds were isolated from methanol extracts in the rhizomes of B. scopulosa and their structures were identified as bergenin （1）, （＋）-catechin （2）, arbutin （3）, 6-O-galloylarbutin （4）, （＋）-catechin-7-O-β-D-glucopyranoside （5）, phenylalanine （6）, succinic acid （7）, protocatechuic acid （8）, gallic acid （9）, methyl gallate （10）, quercetin （11）, hyperoside （12）, rutin （β）, afzelin （14）, chrysophanol-8-O-β-D-glucopyranoside （15）, and 11-O-galloylbergenin （16）. Conclusion Compounds 5--16 are obtained from this plant for the first time.