原发性甲状腺功能减退症12例误诊分析

Cases Analysis of 12 Misdiagnosed Primary Hypothyroidism

目的探讨原发性甲状腺功能减退症的临床特点及误诊情况,以提高诊断率。方法回顾分析1996年至2010年收治的12例被误诊为其他疾病的原发性甲状腺功能减退症患者的临床资料。结果 12例病例中误诊为冠心病、心力衰竭8例,误诊为脑梗塞并血管性痴呆2例,误诊为慢性肾病1例,误诊为贫血1例。结论甲减起病隐匿,初期临床表现不典型,发展至后期可累及机体多个系统,临床表现复杂多样,误诊率高,临床医师应提高对本病的认识,结合临床表现进行必要的甲状腺功能检查,提高诊断率,减少误诊。

Objective To investigate the clinic characters, misdiagnosis situation and reasons, thus to increase the accurate diagnose rate. Methods Make a retrospective analyze on the clinical materials of 12 cases of primary hypothyroidism that were misdiagnosed as other diseases. Results Among the 12 cases of primary hypothyroidism, g cases were misdiagnosed as coronary heart disease, heart failure, 2 cases of cerebral infarction with vascular dementia, 1 case of chronic kidney disease and 1 case of anemia. Conclusions The clinical manifestations of primary hypothyroidism are usually atypical in its early period, and several systems can be involves as the development of the disease, the clinical manifestations are various and complicated in the later period, so the misdiagnose rate is high. Our doctors should improve the understanding of this disease, conduct relevant necessary thyroid function tests combined with clinical manifestations to increase the accurate diagnose rate.