摘要
探讨了超微粉碎对枳实药材中有效成分溶出率的影响。以0.05%磷酸水-甲醇-乙腈为流动相,采用高效液相色谱法(high performance liquid chromatography,HPLC)测定枳实超微粉与药材60目细粉中橙皮苷、柚皮苷和芸香柚皮苷的溶出率。结果表明,枳实超微粉中的橙皮苷、柚皮苷和芸香柚皮苷的溶出率明显高于其60目细粉中三者的溶出率,超微粉碎可增强枳实药材有效成分的溶出。
The effects of ultra - fine powder technique on dissolution rates of the flavonoids in Frutus Aurantii lmmaturus （FAI） were explored. Using 0. 05% H3PO4 water solution -CH3OH -CH3CN as mobile phase, high performance liquid chromatography was employed to determine the concentration of hesperidin, naringin and narirutin in common powdered and ultra - fine powdered FAI. The results were that the dissolution rates of hesperidin, naringin and narirutin in ultra - fine powdered FAI were higher than those of the general powder, and ultra - fine powder technique promoted the dissolution rates of effective constituents of herb medicine.
出处
《广州化工》
CAS
2012年第17期48-50,共3页
GuangZhou Chemical Industry
基金
广东省教育部产学研结合项目(No.2009B090200054)
南华大学人才引进启动基金项目(2011XQD47)
关键词
枳实
超微粉碎
橙皮苷
柚皮苷
Fructus Aurantii Immaturus
ultra - fine pulverization
hesperidin
naringin
