鼻型结外NK/T细胞淋巴瘤MRI和PET/CT表现及比较分析

MRI and PET/CT Findings and their compare analysis of extranodular NK/T-cell ly mphoma nasal type

目的探讨鼻型结外NK/T细胞淋巴瘤MRI和PET/CT的特点。方法回顾性分析56例新诊断鼻型结外NK/T细胞淋巴瘤患者鼻、咽部MRI和/或全身PET/CT的影像学表现,并比较两种检查方法的一致性。结果 48例接受鼻、咽部MRI检查的患者中,原发病灶在鼻腔者有41例,在眼眶、鼻咽部者各有2例,在鼻窦、口咽、喉咽部者各1例,病灶表现为占位性病变或粘膜增厚,向邻近部位播散,多呈等T1等T2信号,内部信号均匀或不均匀,增强后95.8%患者的病灶呈不同程度强化。25例接受PET/CT检查的患者中,原发病灶在鼻腔者有22例,在口咽侧壁者2例,在眼眶者1例,病灶表现为有放射性浓聚的占位性病变,SUVmax为11.1±4.3,有13例患者还发现存在鼻、咽部以外的远处播散病灶。对17例接受了两种检查患者的阳性发现进行比较,两种检查的一致性不佳,差异有显著性。结论鼻型结外NK/T细胞淋巴瘤患者鼻、咽部影像学所见有其鲜明特点,有条件者应积极推荐行全身PET/CT检查。

Objective To explore the characteristics of the MRI and PET/CT findings of extranodular na ture killer/T-cell lymphoma,nasal type. Methods Imaging data of MRI and/or PET/CT from 56 patients who were newly diagnosed as etxranodular NK/T-cell lymphoma,nasal type were analyze d retrospectively.The consistency of the two examinations were also compared and analyzed. Results Of all 48 patients received nose and pharynx MRI examin ation,41 patients’ primary lesions were in nasal cavity.2 patients’ were in orbi tal cavity and 2 were in nasal pharynx.3 patients’ were in paranasal sinuses,ora l pharynx and hypopharynx,respectively.The primary lesions presented as space-o ccupying or thickened mucous membrane and spread to near tissues.Most of the les ions had isointense signal on MRI T1WI on T2WI.The inner signals of the lesions were uniformity or not uniformity.Postcontrast MRI showed slight to moderate enh ancement in 95.8% patients.Of 25 patients received whole-body PET/CT examinatio n,22 patients’ primary lesions were in nasal cavity and 2 patients’ in side wall s of oral pharynx and 1 patient’s in orbital cavity.The primary lesions presente d as space-occupying with condensed radioactivity.The mean maximal standard upt ake value（SUVmax） was 11.1±4.3.13 patients had distant lesions besides primary lesions in nasal and pharynx.Compared the findings of 17 patients who received both of the two examinations,there were no significant consistency between the t wo examinations. Conclusion There were significant characteristics in PET/CT and MRI findings in patients who were newly diagnosed as extranodular NK/T-cell pa tients.PET/CT is recommended when it is available