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益生菌抑制致病菌作用的机制研究进展 被引量:39

Recent advances in mechanism on probiotic bacteria inhibition of pathogens
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摘要 致病菌引起的各种胃肠道疾病对人类健康造成危害,应用益生菌制剂防治致病菌感染,具有安全和减少耐药性等优点,为控制致病菌感染性疾病提供了新的途径。主要从益生菌与致病菌竞争黏附位点、与致病菌的共聚作用及其产生的抗菌物质三个方面综述益生菌抑制致病菌的作用机制。 Pathogens is a major cause of gastrointestinal illness and hazardous to human health. Application of probiotics to the prevention of pathogen infection has received much attention due to safety and decreasing drugtolerance. Here we summarize the recent progress in mechanism of probiotic bacteria inhibition of pathogens including competition for adhesion sites with pathogens, coaggregation with pathogens and production of antimicrobial sub- stances.
出处 《微生物学通报》 CAS CSCD 北大核心 2012年第9期1306-1313,共8页 Microbiology China
基金 中央高校基本科研业务费专项资助项目(No.HIT.NSRIF.2012082) 国家863计划项目(No.2007AA10Z354)
关键词 益生菌 致病菌 抑制 Probiotic bacteria, Pathogen, Inhibition
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