通窍胶囊配合激素治疗急性分泌性中耳炎临床疗效观察

Clinical observation of Tongqiao capsule combined with hormone therapy in acute secretory otitis media

目的探索临床治疗急性分泌性中耳炎有效的中西医结合方法。方法急性分泌性中耳炎患者30例,随机分为治疗组与对照组,各15例。对照组给予通窍胶囊和头孢类抗生素,治疗组在对照组治疗基础上同时给予泼尼松。观察2组患者临床疗效,电测听、声阻抗检查病情恢复情况。结果治疗组有效率为93.3%,对照组有效率为73.3%。与治疗前比较,2组治疗后电测听值均明显降低(P<0.05),治疗组降低的更加明显(P<0.05)。2组治疗前15例患者声阻抗测试均提示为B、C型,治疗组治疗后14例恢复至A型,1例仍为C型;对照组治疗后11例恢复至A型,4例仍为C型。结论通窍胶囊治疗急性分泌性中耳炎临床疗效确切,可能是通过控制炎症及调节机体免疫反应而发挥疗效。

Objective To explore an integrated traditional Chinese and western method in the clinical treatment of acute secretory otitis media.Methods Thirty 30 patients with acute secretory otitis media were randomly divided into treatment group（n=15） and control group（n=15）.The control group received Tongqiao capsule and cephalosporins.The treatment group received prednisone in addition to the treatment of the control group.The clinical efficacy,audiometry,and recovery checked by acoustic impedance in both groups were compared.Results The efficacy rate of the treatment group was 93.3%,and the control group was 73.3%.After treatment,audiometry values of both groups were significantly decreased（P〈0.05）.Compared with the control group,the treatment group had more significant decrease（P〈0.05）.Before treatment,acoustic impedance tests were type B and type C in 15 patients of the two groups.After treatment,14 patients returned to type A with 1 patient being type C in the treatment group and 11 patients returned to the type A with 4 patients being type C in the control group.Conclusion Tongqiao capsule is effective in the treatment of acute secretory otitis,which might be realized through the control of inflammation and regulation of the immune response.