中药单药提取物抗肺癌的研究进展

Effects of Chinese Medicine Extracts on Lung Cancer

肺癌是常见的肺部原发恶性肿瘤,其发病率在近数十年来一直呈上升趋势,是肿瘤工作者亟待解决的重大课题之一。随着靶向药物的问世,易瑞沙等初步显示了较好的临床疗效,但其副作用及如何进一步提高抑瘤率及生存期、生活质量等问题,仍需加强研究。中医药抗肺癌研究近年来亦进步较快,许多中药单药均显示出对肺癌一定的抑制作用,但在药物机制研究方面仍存在着不少问题。现将近年来中药单药提取物抗肺癌的研究进展作一简要综述,以期对进一步临床与实验研究提供帮助。

Lung cancer is a kind of common malignant tumor, frequently occurring in bronchial epithelium. In recent decades, its incidence has been on an upward trend, and it becomes one of major task for medical workers and researchers to resolve. With the advent of target drugs, they initially show a good clinical efficacy. But their side effects are very difficult to avoid. And how to improve tumor inhibition rate and quality of life ,and prolong survival period of those patients who accepted Iressa＇s treatment, are still problems for tumor researchers to resolve. In recent years, many studies of Chinese medicine in treating lung cancer have also made great progress, and a lot of Chinese traditional medicine has showed their inhibitory, effects on lung cancer. But the researches in drug mechanism still have many problems. This article will make a brief review of those researches and would raise some questions for next clinical and experimental research.