摘要
胆道系统恶性肿瘤是一种发病率低、预后差的肿瘤,包括胆管癌、胆囊癌及壶腹部癌。在西方国家胆道系统恶性肿瘤大约占胃肠道肿瘤的4%,东南亚发病率相对较高。在我国,胆道系统恶性肿瘤的发病率并没有明确数字,约占消化道肿瘤的第6位。胆系肿瘤生存率低,预后差,至今尚无有效的化疗方案。目前,关于进展期胆系肿瘤化疗的Ⅱ、Ⅲ期临床试验研究以逐渐开展,化疗方案以吉西他滨为主,单药或联合铂类等药物,得到了明显提高的有效率及生存期。本文就目前胆系肿瘤化疗方面新的进展及成果做综述。
Biliary tract carcinoma is a low incidence and poor prognosis tumor. It includes cholangiocarcinoma, gallbladder and arnpullary carcinoma. In Western countries, hiliary system cancer accounts for about 4% of gastrointestinal cancer, this incidence is rela- tively high in Southeast Asia. In China, the incidence of biliary malignancies has no clear figures and Accounting for 6 of the digestive tract tumors. Biliary tract cancer low survival rate and poor prognosis, so far there is no effective chemotherapy. At present, about ad- vanced biliary tract cancer chemotherapy, Ⅱ, Ⅲ clinical trials research to gradually carry out ,has been significantly improved efficiency and lifetime. Chemotherapy with gemcitabine-based, single agent or in combination with platinumdrugs. This article review on biliary tract cancer chemotherapy, new progress and achievements.
出处
《现代生物医学进展》
CAS
2012年第24期4791-4796,4800,共7页
Progress in Modern Biomedicine
关键词
胆道系统
恶性肿瘤
化疗
进展
Biliary system
Cancer
Chemotherapy
Progress
