产后出血患者血钙浓度与预防使用欣母沛的相关性探讨

Discussion of the correlation between blood calcium concentration of patients with postpartum hemorrhage and prophylactic administration of Hemabate

目的:探讨血钙浓度与欣母沛在预防产后出血中的协同作用。方法:选择2009年12月～2011年7月在常州市妇幼保健院分娩,并用欣母沛预防产后出血患者39例,按血清钙浓度分为两组:正常钙组11例,低血钙组28例。比较两组患者术中出血量,应用欣母沛治疗后24 h累计出血量、产后出血发生率、欣母沛用量。结果:低钙组产妇与正常钙组产妇在术中出血量,应用欣母沛治疗后24 h累计出血量、产后出血发生率、欣母沛使用量方面比较,差异均具有统计学意义(P<0.01)。结论:血钙浓度与欣母沛在预防产后出血中具有协同作用。

Objective： To explore the synergetic effects of blood calcium concentration and Hemabate for preventing postpartum hemorrhage. Methods： A total of 39 patients who gave birth to their babies and were treated with Hemabate to prevent postpartum hemorrhage in the hospital from December 2009 to July 2011 were selected, then they were divided into two groups according to blood calcium concentration ： 11 patients in normal calcium group and 28 patients in low calcium group. The amounts of intraoperative blood loss, 24 - hour ac- cumulative amounts of blood loss after treatment, the incidences of postpartum hemorrhage, and the doses of Hemabate in the two groups were compared. Results： There was statistically significant difference in the amount of intraoperative blood loss, 24 - hour accumulative amount of blood loss after treatment, the incidence of postpartum hemorrhage, and the dose of Hemabate between the two groups （ P 〈 0. 01 ）. Conclusion： The blood calcium concentration and Hemabate have synergetic effects for preventing postpartum hemorrhage.