小儿智力糖浆对注意缺陷多动障碍患儿的疗效观察

Observation on the curative effect of infantile intelligence syrup for treatment of children with attention deficit hyperactivity disorder

目的:观察小儿智力糖浆对注意缺陷多动障碍患儿的疗效。方法 :将86例注意缺陷多动障碍患儿随机分成对照组和治疗组各43例。对照组给予0.3～0.5 mg.kg-1.d-1的利他林片口服,每天2次;治疗组给予10～15 ml/次的小儿智力糖浆口服,每天3次。两组均连续治疗3个月,评价临床疗效,监测不良反应。结果:治疗后两组患儿在品行问题、冲动多动、多动指数等五个方面评分均有明显改善(P<0.05)。治疗组有效率为88.37%,对照组有效率74.42%。治疗组患儿血钙和血锌含量均较治疗前提高(P<0.05);对照组仅血锌水平明显增加。治疗组不良反应发生率低于对照组。结论:小儿智力糖浆治疗注意缺陷多动障碍患儿疗效确切且安全性好,值得推广使用。

Objective： To observe the curative effect of infantile intelligence syrup for treatment of children with attention deficit hyperactivity disorder （ ADHD ） . Methods ： A total of 86 children with ADHD were randomly divided into control group and treatment group, 43 children in each group. The children in control group were treated with oral administration of Ritalin tablets （0. 3 - 0. 5 mg·kg^-1·d^-1 ）, twice a day; the children in treatment group were treated with oral administration of infantile intelligence syrup, 10 - 15 ml per time, three times a day. The children in the two groups were treated consecutively for 3 months, the clinical curative effects were evaluated and the adverse reactions were monitored. Results ： After treatment, the scores of five aspects （ including morality, impulsion, and hyperac- tivity, etc. ） in the two groups increased significantly （P 〈 0. 05 ） . The effective rates in treatment group and control group were 88.37% and 74.42% , respectively. The contents of blood calcium and zinc in treatment group after treatment were statistically significantly higher than those before treatment （ P 〈 0. 05 ） ; while in control group, only blood zinc level increased significantly. The incidence of adverse reactions in treatment group was lower than that in control group. Conclusion： The curative effect and safety of infantile intelligence syrup for treatment of children with ADHD is good, which is worthy to be popularized.