期刊文献+

乙型肝炎相关性肝细胞癌组织中Gli1基因测定的临床意义 被引量:1

Expression of Giil gene in liver tissues from patients with hepatitis B-related hepatocellular carcinoma and its clinical significance
原文传递
导出
摘要 在胚胎发育、组织分化过程中,调控细胞分化与增殖的信号通路,如Hedgehog(HH)在肿瘤的发生发展中起着重要作用H0,而其同源基因SonicHedgehog(SHH)在哺乳动物中作用最为广泛。研究显示,SHH信号通路中的转录因子Glil功能异常可阻碍细胞增殖和分化,影响组织器官发育,提示Glil可能与各种类型癌症的发生相关。
出处 《中华临床感染病杂志》 CAS 2012年第3期170-171,共2页 Chinese Journal of Clinical Infectious Diseases
基金 嘉兴市科技局科研项目(2008AY2033-6)
关键词 肝炎 乙型 肝细胞癌 转录因子Gli1 Hepatitis B Hepatocellular carcinoma Transcription factor Glil
  • 相关文献

参考文献2

二级参考文献43

  • 1[1]Miettinen M,Lasota J.Gastrointestinal stromal tumors--definition,clinical,histological,immunohistochemical,and molecular genetic features and differential diagnosis.Virchows Arch 2001; 438:1-12
  • 2[2]Miettinen M,Sarlomo-Rikala M,Sobin LH,Lasota J.Esophageal stromal tumors:a clinicopathologic,immunohistochemical,and molecular genetic study of 17 cases and comparison with esophageal leiomyomas and leiomyosarcomas.Am J Surg Pathol 2000; 24:211-222
  • 3[3]Miettinen M,Sarlomo-Rikala M,Sobin LH,Lasota J.Gastrointestinal stromal tumors and leiomyosarcomas in the colon:a clinicopathologic,immunohistochemical,and molecular genetic study of 44 cases.Am J Surg Pathol 2000; 24:1339-1352
  • 4[4]Ueyama T,Guo KJ,Hashimoto H,Daimaru Y,Enjoji M.A clinicopathologic and immunohistochemical study of gastrointestinal stromal tumors.Cancer 1992; 69:947-955
  • 5[5]Fletcher CD,Berman JJ,Corless C,Gorstein F,Lasota J,Longley BJ,Miettinen M,O'Leary TJ,Remotti H,Rubin BP,Shmookler B,Sobin LH,Weiss SW.Diagnosis of gastrointestinal stromal tumors:a consensus a pproach.Int J Surg Pathol 2002; 10:81-89
  • 6[6]Appelman HD.Mesenchymal tumors of the gut:historical perspectives,new approaches,new results,and does it make any difference? Monogr Pathol 1990; 31:220-246
  • 7[7]Sanders KM.A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal ract.Gastroenterology 1996; 111:492-515
  • 8[8]Sircar K,Hewlett BR,Huizinga JD,Chorneyko K,Berezin I,Riddell RH.Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors.Am J Surg Pathol 1999; 23:377-389
  • 9[9]Miettinen M,Virolainen M,Maarit-Sarlomo-Rikala.Gastrointestinal stromal tumors--value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas.Am J Surg Pathol 1995; 19:207-216
  • 10[10]Rosai J.Stromal tumors.Rosai and Ackerman's surgical pathology.9th ed.London:Mosby Press,2004:674-680

共引文献18

同被引文献3

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部