期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

不同病原感染的手足口病患儿外周血T淋巴细胞亚群分析 被引量：8

Peripheral blood T lymphocyte subsets in children with hand, foot and mouth diseases induced by different pathogens
原文传递
导出
摘要 手足口病是由多种肠道病毒引起的急性传染病，病原以肠道病毒71型（EV7I）及柯萨奇病毒A16型（CoxA16）最为常见。其中EV71型感染发生神经系统严重并发症较多见，而CoxA16型所致临床表现多较轻。我们于2009年初步研究发现手足口病患儿机体免疫细胞改变。
作者 刘亚敏 李颖 任彦 平蕾 杨悦杰
机构地区 天津市传染病医院感染科
出处 《中华临床感染病杂志》 CAS 2012年第3期175-176,共2页 Chinese Journal of Clinical Infectious Diseases
关键词 手足口病 病原 T淋巴细胞亚群 免疫 Hand, foot and mouth disease Pathogen T lymphocyte subsets Immunity
分类号 R725.1 [医药卫生—儿科]
  • 相关文献

参考文献11

二级参考文献36

  • 1范晓晨,都鹏飞.血糖监测对小儿手足口病病情和预后判断的价值分析[J].安徽医学,2009,30(3):253-255. 被引量：20
  • 2随素敏,都鹏飞.机械通气治疗重症手足口病合并急性肺水肿10例临床分析[J].安徽医学,2009,30(3):260-261. 被引量：21
  • 3张代民,张莹,许会彬.105例小儿患者手足口病实验室检查结果分析[J].实用医药杂志,2004,21(11):982-983. 被引量：17
  • 4Wang SM, Lei HY, Huang KJ, et al. Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema. J Infect Dis,2003,15:564-570.
  • 5Chang LY, Hsiung CA, Lu CY, et al. Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71. Pediatr Res, 2006, 60:466-471.
  • 6Lin TY, Chang LY, Huang YC, et al. Different proinflammatory reactions in fatal and non-fatal enterovirus 71 infections: implications for early recognition and therapy. Acta Paediatr, 2002, 91:632-635.
  • 7Lin TY, Hsia SH, Huang YC, et al. Proinflammatory cytokine reactions in enterovirus 71 infections of the central nervous system.Clin Infect Dis,2003, 36: 269-274.
  • 8Wang SM, Lei HY, Yu CK,et al. Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71- associated brainstem encephalitis. J Infect Dis, 2008, 198 : 1002- 1006.
  • 9Lekkou A, Karakantza M, Mouzaki A, et al. Cytokine production and monocyte HLA-DR expression as predictors of outcome for patients with community-acquired severe infections. Clin Diagn Lab Immunol,2004,11 : 161-167.
  • 10Wang SM, Lei HY, Huang MC, et al. Modulation of cytokine production by intravenous immunoglobulin in patients with enterovirus 71-associated brainstem encephalitis. J Clin Virol, 2006, 37:47-52.

共引文献211

同被引文献97

  • 1党月兰,张玉琳.抗感颗粒剂的抗炎作用[J].甘肃中医学院学报,1996,13(4):26-28. 被引量：2
  • 2Sallusto F, Lanzavecchia A. Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity [ J ]. Eur J Immu- nol, 2009, 39(8): 2076-2082.
  • 3Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 [ J]. Nat Immunol, 2005, 6(11) : 1133-1141.
  • 4Sfanos KS, Bruno TC, Maris CH, et al. Phenotypic analysis of prostate-infiltrating lymphocytes reveals Th17 and Treg skewing [ J]. Clin Cancer Res, 2008, 14 ( 11 ) : 3254-3261.
  • 5Zhou L, Lopes JE, Chong MM, et al. TGF-beta-indueed Foxp3 inhibits T(H) 17 cell differentiation by antagonizing RORgammat function[ J]. Nature, 2008, 453 (7192) : 236-240.
  • 6Xu L, Kitani A, Fuss I, et al. Cutting edge: regulatory T cells in- duce CD4+ CD25-Foxp3- T ceils or are self-induced to become Th17 cells in the absence of exogenous TGF-beta[ J]. J Immunol, 2007, 178( 11 ) : 6725-6729.
  • 7Wing K, Fehervari Z, Sakaguchi S. Emerging possibilities in the development and function of regulatory T cells [ J ]. Int Immunol, 2006, 18(7): 991-1000.
  • 8Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 [ J]. Nat Immunol, 2005, 6(11) : 1133-1141.
  • 9Ghilardi N, Kljavin N, Chen Q, et al. Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice [J]. J Immunol, 2004, 172(5) : 2827-2833.
  • 10Parham C, Chirica M, Timans J, et al. A receptor for the het- erodimeric cytokine IL-23 is composed of IL-12Rbetal and a novel cytokine receptor subunit, IL-23R [ J]. J Immtmol, 2002, 168 ( 11 ) : 5699-5708.

引证文献8

二级引证文献52

中华临床感染病杂志
2012年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部