结直肠高危腺瘤患者危险因素的调查

Survey of risk factors for colorectal high-risk adenoma

目的对结直肠高危腺瘤患者进行调查,以发现其高危影响因素。方法调查对象为2010年7月～2011年7月来我院就诊的237例结肠腺瘤病例,均为病理诊断确诊,所有调查对象中高危腺瘤及低危腺瘤的患者例数分别为129例、108例。采用统计学方法对其影响因素进行分析。结果与低危腺瘤组比较,高危腺瘤组患者的吸烟、饮酒、糖尿病、高脂血症患者所占比例均较大,冠心病患者所占比例较小,两组间差异有统计学意义(P<0.05)。将所有的影响因素均使用Logistic回归分析发现,患者的年龄、糖尿病及高脂血症为高危腺瘤患者发病的危险因素。结论结直肠高危腺瘤发病受患者的年龄、是否患有糖尿病及其高脂血症的影响。

Objective To survey the high-risk adenomas of the colorectal patients and find the high-risk impact factors. Methods A total of 237 cases with the colon adenoearcinoma were selected from July 2010 to July 2011 in our hospital, they were divided into the high-risk adenoma patients group （n = 129 cases） and the low-risk adenoma patients group （n = 108 cases）. We analyzed the influencing factors with statistical methods. Results Compared with low-risk adenoma group, smoking, drinking, diabetic patients of the high-risk adenomas were higher, coronary heart disease patients proportion of high-risk adenomas was lower, and there was significant difference between two groups （P 〉 0.05）. All factors affecting Logistic regression analysis showed the patient＇s age, diabetes, hyperlipidemia in patients with risk factors for high-risk adenoma. Conclusion Colorectal high-risk adenomas are affected by the age of the patients, diabetes and hyperlipidemia.