医用三氧治疗急性期大面积脑梗死疗效及对血脂、血氧饱和度的影响

The effects of medical ozone on acute massive cerebral infarction and serum lipids and blood oxygen saturation

目的探讨医用三氧治疗急性期大面积脑梗死的临床疗效,观察医用三氧对血脂、血氧饱和度的影响。方法将60例急性期大面积脑梗死患者随机分为医用三氧治疗组和对照组,治疗组在常规药物和康复治疗基础上行医用三氧治疗,对照组为常规药物和康复治疗,两组患者治疗前和治疗2周后应用NIHSS(美国国立卫生研究院脑卒中量表)神经功能缺损评分,治疗前后检测血脂和血气分析血氧饱和度。结果两组治疗2周后与治疗前比较神经功能评分均有明显改善,治疗后治疗组的神经功能缺损评分与对照组比较差异有统计学意义(P<0.05);治疗组总有效率73.3%,对照组总有效率66.7%,治疗组治疗后低密度脂蛋白胆固醇下降(P<0.05),血氧饱和度提高(P<0.05),对照组的血脂和血氧饱和度无变化。结论医用三氧能明显提高急性期大面积脑梗死患者的疗效,同时能降低低密度脂蛋白胆固醇,提高血氧饱和度。

Objective To explore medical ozone to treat a large area of cerebral infarction in the acute phase in clinic and observe the impact of medical ozone on serum lipids, blood oxygen saturation. Methods Sixty cases of acute phase cerebral infarction were randomly divided into medical oxygen treatment group and control group. Treatment group was added ozone treatment into conventional drug and rehabilitation treatment. Control group was only the conventional drug and rehabilitation treatment. Before treatment and after 2 weeks two group patients applied the NIHSS （National Institutes of Health Stroke Scale） neurological deficit scores. Test lipids and blood gas analysis of oxygen saturation before and after treatment. Results After two weeks treatment, neurological function scores were improved significantly comparing with before. And the neurological deficit scores was very different with control group＇s score （P 〈 0.05）. Total efficiency of treatment group was 73.3% and total efficiency of control group was 66.7%. After treatment, low-density lipoprotein cholesterol of treatment group decreased （P 〈 0.05） and oxygen saturation of treatment group increased （P 〈 0.05）. While oxygen saturation of control group didn＇t change. Conclusion Medical ozone can improve the efficacy of massive cerebral infarction in patients with acute phase significantly, while it can decrease LDL cholesterol and imDrove the oxwen saturation.