胸腔镜与传统手术对非小细胞肺癌的临床疗效分析

Clinical analysis of video-assisted thoracic surgery versus traditional thoracotomy for non-small cell lung cancer

目的探讨电视胸腔镜手术(VATS)较传统开胸手术在非小细胞肺癌(NSCLC)治疗中的优势。方法将80例NSCLC患者随机分为VATS组和S组各40例,术后比较两组相关指标。结果 VATS组较S组手术时间长、术中出血量少、留置胸管时间短、止痛时间及住院时间短(P<0.01),清扫淋巴结个数(P>0.05);疼痛时间明显低于S组(P<0.05)。术后第1、5天血清CRP均较术前明显升高(P<0.05),VATS组明显低于同时间点S组(P<0.05)。结论 VATS手术可作为NSCLC患者的推荐治疗方法。

Objective To investigate the advantages of video-assisted thoracoscopic surgery （VATS） compared with conventional thoracotomy in the treatment of non-small cell lung cancer （NSCLC）. Methods Eighty cases with NSCLC were collected and divided into VATS group （n = 40,undergone complete video-assisted thoracoscopic pneumonectomy） and S group （n = 40,undergone traditional open pneumonectomy）. The indexes of patients in the two groups were compared after operation. Results Compared with S group,the mean operative time was longer, the bleeding loss, chest tube lien time, postop erative pain time were shorter in VATS group （P 〈 0.01）. Besides, the number of lymph node dissection was not significantly different between the two groups （P 〉 0.05）. Pain time of patients in S group was longer than those in VATS group （P 〈 0.05）. Levels of postoperative serum CRP of patients in the two groups were both higher than those before operation （P 〈 0.05）, and levels of serum CRP of patients in VATS group on the first and fifth day after operation were markedly lower than those at the same time point in S group （P 〈 0.05）. Conclusion VATS can be recommended as a treatment of lung cancer.