爱尔碘皮肤消毒剂对生物膜阳性致病菌的体外杀菌试验

In vitro bactericidal experiment of ai′erdian skin antiseptic on positive pathogenic bacteria

目的了解爱尔碘皮肤消毒剂对生物膜阳性致病菌的最小杀菌浓度。方法将所有受试菌进行生物膜形成检测,再用对倍稀释法,以爱尔碘皮肤消毒剂不同浓度对生物膜阳性致病菌作用不同时间,观察杀菌效果。结果金黄色葡萄球菌、大肠埃希菌和铜绿假单胞菌生物膜形成阳性率分别为54.3%、47.3%和57.0%;爱尔碘皮肤消毒剂在有效碘含量为9.203×10-4 mg/L时,作用1min后,可将所有受试菌株全部杀灭。结论爱尔碘皮肤消毒剂对生物膜阳性致病菌具有高效的杀菌性。

OBJECTIVE To study the minimum bactericidal concentration of ai′erdian skin antiseptic on positive pathogenic bacteria.METHODS All the pathogenic bacteria producing biofilm were tested,then different concentrations of ai′erdian skin antiseptic were applied to the biofilm-positive pathogens for difference period of time,the sterilization effects were observed.RESULTS The positive rates of the formation of biofilm of Staphylococcus aureus,Escherichia coli and Pseudomonas aeruginosa were 54.3%,47.3% and 57.0%;All of the positive pathogenic bacteria were eradicated with the effective content of iodine of 9.203×10-4 mg/L for 1min.CONCLUSION Ai′erdian skin antiseptic is a kind of strong and effective disinfectant on biofilm positive pathogenic bacteria.