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Lp-PLA2及其基因多态性与冠心病关联研究 被引量:7

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摘要 冠心病是现代社会严重危害人类健康.影响人们生活质量的一种心血管疾病。近年有研究发现,冠状动脉粥样硬化是一种脂质代谢紊乱性疾病,炎症反应诱使粥样硬化斑块不稳定,进而发生破裂,参与冠心病的发生发展过程。脂蛋白相关磷脂酶A2(Lp-PIJA2)是新近发现的一种与冠状动脉粥样硬化斑块相关的炎症标记物,可能与动脉粥样硬化(AS)的形成相关,并且是冠心病的一个独立的危险预测因子.近年来成为动脉粥样硬化领域的研究热点。
作者 马莎 王玉璟
出处 《实用医学杂志》 CAS 北大核心 2012年第17期2981-2983,共3页 The Journal of Practical Medicine
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