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干细胞宫内移植研究进展 被引量：1

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摘要 随着人类产前诊断技术和分子遗传学研究的进步，许多遗传疾病（如Fanconi’s贫血，地中海贫血、红细胞丙酮酸激酶缺乏症等血红蛋白病，血友病及免疫系统缺陷等）在早期妊娠阶段就能得到诊断。早期妊娠阶段的胎儿体重与成人间的差异较大，少量干细胞即可对其起到治疗作用；此外，胎儿的胸腺尚在发育中，适当的抗原呈递就能诱导其终身耐受该抗原。若此时进行宫内治疗，可将疾病的危害程度降至最低，并大大减轻社会和患者家庭的负担。以下就干细胞宫内移植的研究现状作一综述。
作者 杨辰敏 薛燕 曾凡一
机构地区 上海交通大学医学院 上海交通大学医学院附属瑞金医院妇产科
出处 《上海医学》 CAS CSCD 北大核心 2012年第7期647-650,共4页 Shanghai Medical Journal
关键词 宫内移植 干细胞 Fanconi 酮酸激酶缺乏症 地中海贫血 免疫系统缺陷 诊断技术 遗传疾病
分类号 R714.5 [医药卫生—妇产科学]
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参考文献40

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二级参考文献12

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上海医学
2012年 第7期

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