六元瓜环与二氯化-1,8-二(2-苯并咪唑基)辛烷的自组装模式

Self-assemblied Binding Mode of Cucurbit[6]uril with 2,2′-(Octane-1,8-diyl)dibenzimidazolium Dichloride

采用1H NMR、荧光光谱和紫外吸收光谱法考察了主体六元瓜环与合成客体二氯化-1,8-二(2-苯并咪唑基)辛烷的自组装模式.结果表明,六元瓜环能与二氯化-1,8-二(2-苯并咪唑基)辛烷发生相互作用,瓜环包结客体分子的苯并咪唑基团,烷基链置于瓜环端口外侧.自组装模式与主客体的摩尔比密切相关.当主客体的摩尔比为1∶1时,1个瓜环包结客体分子的一端苯并咪唑基团形成棒槌形的包结配合物;当主客体的摩尔比为2∶1时,2个瓜环分别包结客体分子的两端苯并咪唑基团形成哑铃型的主客体包结配合物.

The self-assemblied binding modes of cucurbit [ 6 ] uril （ Q [ 6 ] ） with 2,2＇- （ octane-l, 8-diyl） dibenzimidazolium dichloride （SBO） was investigated by means of H NMR, fluorescence emission and UV-Vis spectra. The experiment results revealed that the host Q [ 6 ] prefered to including the aromatic benzoimidazolyl moieties of the protonated SBO at a lower molar ratio of Q [ 6 ] to guest less than 1 in water medium, at higher molar ratios of Q[6 ] to guest or in water medium, a chain shape guest could be borne two Q [ 6 ] molecules and form a dumbbell shape inclusion complex. The study may provide information in drug delivery, designment of molecular knots, machines and switches.