机械通气相关性肺炎相关因素logistic回归分析

Logisticregression analysis of related factors for mechanical ventilation correlated pneumonia

目的探讨机械通气相关性肺炎相关因素及预防对策。方法选择机械通气治疗的290例患者作为研究对象,对机械通气相关性肺炎相关因素进行单因素及logistic多因素回归分析。结果 290例患者发生机械通气相关性肺炎80例,占27.6%,单因素检验显示10个变量,差异有统计学意义(P<0.05),多因素非条件logistic回归分析显示,胃内容物反流(OR=3.86)、机械通气应用时间长(OR=3.50)、应用抗酸剂(OR=2.97)、APACHEⅡ评分高(OR=2.85)是机械通气相关性肺炎独立危险因素。结论机械通气相关性肺炎发生率较高,与多种因素有关,通过预防胃内容物反流、缩短机械通气时间、避免使用抑酸剂、提高机体免疫功能,可减少机械通气相关性肺炎的发生率。

OBJECTIVE To explore the related factors for mechanical ventilation correlated pneumonia and prevention countermeasures. METHODS A total of 290 patients who underwent mechanical ventilation were selected as the research subjects, the univariate factor analysis and logistic regression analysis of the related factors for mechanical ventilation correlated pneumonia were performed. RESULTS Of 290 patients, mechanical ventilation correlated pneumonia occurred in 80 cases, accounting for 27. 6%, the single factor examination showed that the differences among 10 variables were unconditional logistic regression analysis indicated that statistically significant （P〈0. 05）, multiple factors the reverse flow stomach content （OR = 3. 86）, long duration of mechanical ventilation （OR=3.50）, the application of antacids （OR = 2.97）, and high APACHE Ⅱscore （OR = 2.85） were the independent risk factors for mechanical ventilation pneumonia. CONCLUSION The incidence of the mechanical ventilation correlated pneumonia is relatively high, which is related to many factors; the incidence of mechanical ventilation correlated pneumonia can be reduced through preventing the stomach content reflux, shortening the duration of mechanical ventilation, avoiding the use of mechanical ventilation acid agents, and enhancing the immune function.