LEEP治疗宫颈上皮内瘤变临床疗效观察

Clinical effect observation on curing cervical intraepithelial neoplasia by loop electrical excision procedure

【目的】观察电环切除术治疗宫颈上皮内瘤样病变的临床疗效。【方法】对经细胞学、阴道镜和病理学诊断为CIN的患者进行宫颈电环切除术治疗。观察手术时间、术后病理特点、治疗效果及术后并发症。【结果】宫颈电环切除术治疗宫颈上皮内瘤变平均手术时间7.5分钟,治愈率96.2%,术前、术后病理诊断一致的占53.16%(84/158);术后病理诊断级别下降的占41.14%(65/158),术后病理诊断级别上升的占5.70%(9/158)。术前病理诊断级别高,可导致CIN治疗过度。术后并发症的发生与手术操作技巧有关。【结论】宫颈电环切除术治疗宫颈上皮内瘤样病变安全有效,手术时间短,并发症少,严格手术指证,规范手术操作,可获得满意疗效。

[Objective] Observe the clinical effect of loop electrical excision procedure to cure cervical intraepithelial neoplasia. [Method] Treat the CIN patients who have been diagnosed by cytology, colposcopy and pathologic with loop electrical excision procedure and observe the time of operation, features of pathological grade after operation, effects and complication. [ Result] Average time cost of cervical loop electrical excision procedure is 7min30sec, with 96.2% cared. The pathologic grade of same diagnosis before and after operation occupy 53.16% （84/158）; pathologic grade of downgrade diagnosis occupy 41.14（65/158）; pathologic grade of upgrade diagnosis occupy 5.70% （9/158）. High level in pathological diagnosis leads to excessive treatment. Complication occurrence related with operative skill. [Conclusion] Cervical loop electrical excision procedure is effective, with short time of operation and limited complication. We could receive satisfied result if operator does strictly with instruction of operation.