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人博卡病毒研究进展 被引量：1

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摘要 2005年，瑞典的Allander等人^[1]采用宿主DNA消除、随机PCR扩增、高通量测序和生物信息学知识相结合的方法，在呼吸道感染患儿的鼻咽抽吸物中发现了一种新的细小病毒——人博卡病毒（hu．man bocavirus，HBoV）。随后，世界上许多国家陆续报道了在呼吸道感染患儿中检测出HBoV，
作者 赵慧 钱渊
机构地区 北京协和医学院研究生院 首都儿科研究所病毒研究室
出处 《国际病毒学杂志》 2012年第4期178-180,共3页 International Journal of Virology
关键词 人博卡病毒 呼吸道感染 免疫反应
分类号 R72 [医药卫生—儿科]
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参考文献26

  • 1Allander T, Tammi M T, Eriksson M, et al. Cloning of a human parvovirus by molecular screening of respiratory tract samples. Proc Natl Acad Sci U S A,2005,102(36) :12891-12896.
  • 2Dijkman R, Koekkoek S M, Molenkamp R, et al. Human bocavirus can be cultured in differentiated human airway epithelial cells. J Viro1,2009,83 ( 15 ) :7739-7748.
  • 3Kapoor A, Simmonds P, Slikas E, et al. Human bocaviruses are highly diverse, dispersed, recombination prone, and prevalent in enteric infections. J Infect Dis,2010,201 (11 ) :1633-1643.
  • 4Arthur J L, Higgins G D, Davidson G P, et al. A novel bocavirus associated with acute gastroenteritis in Australian children. PLoS Pathog ,2009,5 ( 4 ) : e1000391.
  • 5Zhi N, Mills I P, Lu J, et al. Molecular and functional analyses of a human parvovirus B19 infectious clone demonstrates essential roles for NS1, VP1, and the 11-kilodalton protein in virus replication and infectivity. J Virol,2006,80 ( 12 ) :5941-5950.
  • 6QuXW, Liu W P, QiZY, etal of human bocavirus VP1 unique Commun,2008,365( 1 ) :158-163.
  • 7Phospholipase A2-1ike activity region. Biochem Biophys Res Pozo F, Garcia-Garcia M L, Calvo C, et al. High incidence of human bocavirus infection in children in Spain. J Clin Virol, 2007, 40(3 ) :224-228.
  • 8Martin E T, Taylor J, Kuypers J, et al. Detection of bocavirus in saliva of children with and without respiratory illness. J Clin Microbiol,2009,47(12) :4131-4132.
  • 9Lu X, Gooding L R, Erdman D D. Human bocavirus in tonsillar lymphoeytes. Emerg Infect Dis,2008,14 ( 8 ) : 1332-1334.
  • 10Christensen A, Nordbo S A, Krokstad S, et al. Human bocavirus in children: mono-deteetion, high viral load and viraemia are as-sociated with respiratory tract infection. J Clin Virol, 2010,49 (3) :158-162.

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  • 1World Health Organization. Burden of disease in DALYs by cause, sex and mortality stratum in WHO Regions, estimates for 2001.[EB/OLJ. 2002[2012-12-26J. http://www. who. inti whr/2002/whr2002_annex3. pdf.
  • 2Cant AJ, Gordon SB, Read RC, et al. Respiratory infections.J Med Microbiol, 2002, 51 ( 11 ) : 903 -914.
  • 3Ren L, Gonzalez R, Wang Z, et al. Prevalence of human respira?tory viruses in adults with acute respiratory tract infections in Bei?jing, 2005-2007. Clin Microbiol Infect, 2009, 15 (12): 1146- 1153.
  • 4Dumke R, Schurwanz N, Lenz M, et al. Sensitive detection of Mycoplasma pneumoniae in human respiratory tract samples by op?timized real-time PCR approach.J Clin Microbiol, 2007,45(8): 2726-2730.
  • 5World Health Organization. Recommended composition of influ?enza virus vaccines for use in the 2012-2013 northern hemisphere influenza season.[EB/OLJ. (2012-2)[2012-12-26J . http:// www. who. intlinfluenzal vaccines/ virus/ recommendationsl201202 _ recommendation. pdf.
  • 6Liu WK, Chen DH, Liu Q, et al. Detection of human bocavirus from children and adults with acuterespiratory tract illness in Guang zhou, southern China. BMC Infect Dis, 2011, 11: 345.
  • 7Bastien N, Brandt K, Dust K, et al. Human Bocavirus infec?tion, Canada. Emerg Infect Dis, 2006, 12 (5) : 848-850.
  • 8Qu XW, Duan ZJ, Qi ZY, et al. Human bocavirus infection, People's Republic of China. Emerg Infect Dis, 2007, 13 ( 1 ) : 165-168.
  • 9Kaplan NM, Dove W, Abu-Zeid AF, et al. Human bocavirus in?fection among children,Jordan. Emerg Infect Dis, 2006, 12 (9) : 1418-1420.
  • 10Deng Y, Gu X, Zhao X, et al. High viral load of Human Bo?cavirus correlates with duration of wheezing in children with se?vere lower respiratory tract infection. PLOS One, 2012, 7 (3) : e34353.

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国际病毒学杂志
2012年 第4期

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