胆胃舒颗粒治疗胆汁反流性胃炎临床研究

Danweishu Granule in the Treatment with Bile Reflux Gastritis

目的:观察胆胃舒颗粒治疗胆胃郁热型胆汁反流性胃炎的临床疗效。方法:120例患者随机分为治疗组60例和对照组60例。治疗组采用三九免煎中药胆胃舒颗粒口服,对照组口服多潘立酮片、雷尼替丁、硫糖铝,两组均连续治疗4周为1疗程。结果:治疗组痊愈43例,显效8例,有效4例,无效5例,有效率为91.7%。对照组痊愈33例,显效4例,有效2例,无效21例,有效率为65.0%。两组有效率比较,差异有统计学意义(P<0.05)。结论:胆胃舒颗粒能明显改善胆汁反流性胃炎患者临床症状及胃镜学指标,阻止胆汁反流,改善胃黏膜的病变。

Objective：Observe the clinical curative effect of Danweishu granule in the treatment of biliary and stomach stagnated heat type bile reflux gastritis. Methods ：120 eases were randomly divided into the treatment group and control group ,60 cases of each group. The treatment group was given Danweishu granule and the control group was given Domperidone Maleate Tablets, Ranitidine and ulcer- lmin ,4 weeks as one course of treatment. Resuhs：In the treatment group ：43 cases recovery ,8 eases markedly improved,4 cases effec- tive,5 eases ineffective, the effective rate was 91.7 %. In the control group ：33 cases recovery ,4 cases markedly improved,2 eases effec- tive,21 cases ineffective, the effective rate was 65.0%. Compared the effective power, the difference was statistically significant （P 〈 0. 05 ）. Conclusion ： Danweishu granule can obviously improve clinical symptoms of bile reflux gastritis and gastroseope index, prevent bile regurgitation and improve pathological changes of stomach lining with safe, reliable and easy to accept.