沙丁胺醇和丙酸氟替卡松雾化吸入治疗慢性阻塞性肺病急性加重疗效分析

Clinical Analysis of Treatment Chronic Obstructive Pulmonary Disease Aggravated by Salbutamol and Fluticasone Propionate Carcassonne Atomization Inhalation

目的观察沙丁胺醇和丙酸氟替卡松雾化吸入治疗慢性阻塞性肺病急性加重的疗效。方法将29例慢性阻塞性肺疾病急性加重的患者随机分成两组,对照组28例,常规给予抗生素及相应对照治疗;实验组29例,在对照组的基础上沙丁胺醇与丙酸氟替卡松雾化吸入治疗。用药后观察实验组及对照组临床效应、不良反应及住院时间。结果实验组及对照组每组治疗前后1周临床症状评分差异有显著性,实验组FEV1/预计值,PEF/预计值及住院时间较对照组治疗差异有显著性,并且未发现不良反应。结论在常规抗炎、祛痰等治疗基础上加用沙丁胺醇和丙酸氟替卡松联合雾化治疗一周后,患者临床症状评分及肺功能均明显改善,明显缩短了治疗疗程和住院时间,且无严重不良反应。

To observe salbutamol inhaled fluticasone atomization treatment of acute exacerbation of chronic obstructive pulmona- ry disease （COPD） and propionic acid fluoride. Methods： The 29 cases of patients with acute exacerbation of chronic obstructive pulmonary disease were randomly divided into two groups, the control group, 28 patients routinely given antibiotics and the corre- sponding control treatment; experimental group of 29 patients in the control group on the basis of Carcassonnc atomization inhalation of salbutamol and fluticasone propionate treatment. Observe the clinical effect of the experimental and control groups, adverse reac- tions, and hospitalization time after treatment. Results ： The experimental group and the control group, each group one week clinical symptom score difference before and after treatment, the experimental group FEV1 / predicted value, PEF / expected value and the length of hospital stay compared with the control group treatment difference was significant, and found no adverse reactions. Conclu- sion ： The addition of the treatment on the basis of the conventional anti - inflammatory, expectorant the salbutamol and propionic acid fluoride behalf Carcassonne joint atomization after a week of treatment, patients with clinical symptom scores and lung function improved significantly, significantly shortening the course of treatment and hospitalization time, and no serious adverse reaction.