奥美拉唑联合奥曲肽治疗消化性溃疡急性上消化道出血的疗效观察

Curative effect observation of omeprazole combined octreotide in peptic ulcer with acute upper gastrointestinal hemorrhage

目的探讨消化性溃疡急性上消化道出血患者联合应用奥曲肽与奥美拉唑治疗的临床效果。方法选取因消化性溃疡引起的上消化道出血患者120例,随机分为观察组与对照组,每组60例,观察组给予奥曲肽与奥美拉唑治疗,对照组仅给予奥美拉唑治疗,比较两组的止血情况,并观察不良反应。结果观察组的止血总成功率显著高于对照组(P均<0.01);两组各出现1例轻微不良反应,未予处理自行好转。结论联合应用奥曲肽与奥美拉唑在消化性溃疡急性上消化道出血患者中疗效确切。

Objective To investigate the curative effect of omeprazole combined octreotide in peptic ulcer with acute upper gastrointestinal hemorrhage. Methods One hundred and twenty cases of patients with a cute upper gastrointestinal hemor- rhage by peptic ulcer were selected and randomly divided into observation group and control group, there was 60 cases in each group, patients in observation group were treated with octreotide and omeprazole, patients in control group were treat- ed with omeprazole, rates of hemostasis and adverse reactions were comtrasted between control group and observation group. Results Achievement ratio of henaostasis was higher in observation group than that in control group （P 〈 0.01）; there was mild adverse reactions in patients in each group, and were not given improvement treatment but better on its own. Conclusion Octreotide combined omeprazole in treatment of acute upper digestive tract hemorrhage with peptic ulcer pa- tients has good curative effect.