拉贝洛尔治疗重度妊娠高血压综合征的临床观察

Clinical observation of labetalol in the treatment of severe pregnancy induced hypertension syndrome

目的研究分析拉贝洛尔对重度妊娠高血压综合征的临床疗效。方法抽取76例患有重度妊娠高血压综合征的临床确诊患者,将其分为A、B两组,平均每组38例。A组患者采用硫酸镁进行治疗,B组患者采用硫酸镁与拉贝洛尔联合治疗。结果服药后B组患者的总有效率为94.7%,A组患者的总有效率为81.6%,B组明显优于A组,且差异具有统计学意义(P<0.05)。B组患者在用药前后的血压改善幅度明显高于A组,且差异具有统计学意义(P<0.05)。结论拉贝洛尔治疗重度妊娠高血压综合征的临床效果非常明显。

Objective To research and analyze the clinical effect of labetalol in the treatment of severe pregnancy induced hypertension syndrome （PIH）. Methods Seventy-six cases of patients with severe PIH diagnosed by clinic were selected and divided into group A and B, each group had 38 cases. Patients of group A were treated with magnesium sulfate, while patients of group B were treated with magnesium sulfate combined with labetalol. Results After taking medicine, the total effective rate of group B was 94.7%, the total effective rate of group A was 81.6%, group B was better than that of group A, the difference was statistically significant （P 〈 0.05）. Improvement range of blood pressure before and after taking medicine of group B was significantly higher than that of group A, the difference was statistically significant （P 〈 0.05）. Conclusion The clinical effect of labetalol in the treatment of patients with severe PIH is significant.