超声引导下无水乙醇联合米非司酮在异位妊娠保守治疗中的临床应用

Clinical application on ultrasonic monitoring in the conservative treatment of ectopic pregnancy

目的探讨超声引导下无水乙醇联合米非司酮在异位妊娠保守治疗中的临床价值。方法选取本院2009年10月～2011年11月收治的异位妊娠患者85例,根据不同的保守治疗方法分为两组,采用甲氨蝶呤和米非司酮治疗的患者42例为对照组,超声引导下采用无水乙醇和米非司酮治疗的患者43例为观察组,超声监测患者的包块吸收情况和腹腔内出血情况,比较两组患者保守治疗后的临床疗效。结果观察组附件包块消失时间小于对照组,观察组治愈率和输卵管通畅率均高于对照组,但差异均无统计学意义(P>0.05)。观察组并发症发生率(7.0%)明显低于对照组(28.6%),差异有统计学意义(P<0.05)。结论超声监测在异位妊娠保守治疗中具有重要的临床价值,操作方法简便且安全有效,值得临床推广使用。

Objective To investigate the clinical value on ultrasonic monitoring in the conservative treatment of ectopic pregnancy. Methods Eighty-five patients with ectopic pregnancy were selected in the hospital from October 2009 to November 2011. According to the different methods of conservative treatment, patients were divided into two groups. Forty- two patients used methotrexate and mifepristone in the treatment as the control group, 43 patients used ethanol and mifepristone in the treatment under ultrasound guidance as the observation group. Mass absorption and intraperitoneal hemorrhage of patients were monitoried by ultrasonic. Clinical efficacy was compared between two groups after conservative treatment. Results Attachment mass disappearance time in the observation group was less than that in the control group. Cure rate and tubal patency rate in the observation group were higher than those in the control group, but the differences were not statistically significant （P 〉 0.05）. Complication rate in the observation group 7.0% was significantly lower than that in the control group （28.6%）, while the difference was statistically significant （P 〈 0.05）. Conclusion Ultrasonic monitoring in the conservative treatment of ectopic pregnancy has important clinical value. The operation is simple, safe, effec- tive. That is worth for clinical use.