30例胃肠道间质瘤CT表现、病理与预后分析

Gastrointestinal stromal tumor imaging analysis:correlation with pathological characteristics and follow-up of 30 cases

目的探讨胃肠道间质瘤CT检查的临床价值。方法对30例经证实为胃肠道间质瘤患者的CT表现、病理特征及随访情况进行回顾性分析。结果 30例GIST患者中病变位于胃部17例,小肠8例,结肠5例。良性16例,恶性14例。肿瘤病理危险度评估:极低危8例(27%)、低危7例(23%),中危6例(20%),高危9例(30%)。CT影像、预后与病理对照分析,肿瘤形态不规则、浸润性生长、严重瘤内坏死、强化程度和较差预后更多见于高危险度胃肠道GIST(P<0.05);肿瘤生长部位与GIST的病理危险度之间没有显著相关性(P>0.05)。结论 CT扫描对GIST诊断有特征性影像表现,在定位、定性等方面有较大的临床价值。

Objective To investigate the value of CT scan in gastrointestinal stromal tumor（GIST）. Methods Thirty cases of GIST were retrospectively analyzedfor CT findings, pathological characteristics and follow-up investigated the potential re lations among them. Results There were 17 gastric GIST, 8 intestinal GIST and 5 colonal GIST. 16 cases of GIST were of high grade malignancy, the other 14 cases were of low grade malignancy. Pathological risk assessment revealed that 8 cases were at very low risk, 7 cases at low risk, 6 cases at middle risk and 9 cases at high risk. According to the CT image, as well as prognositic and pathological analysis, irregular tumor morphology, invasive growth, severe tumor necrosis, degree of CT enhancement and poor prognosis were more seen in the high risk GIST. No significant correlations between tumor loca tion and pathological risk of GIST were found. Conclusion CT scan for GIST had characteristic imaging in location and na ture, thus this method has greater clinical value.