胃溃疡切除修补术联合药物治疗胃溃疡穿孔68例疗效分析

Resection and repair surgery joint drug for gastric ulcer perforation: efficacy analysis of 68 cases

目的探讨胃溃疡切除修补术联合药物治疗胃溃疡穿孔的临床效果。方法将我院收治的68例胃溃疡穿孔患者随机分为对照组和观察组,对照组采用胃大部分切除术治疗,观察组采用胃溃疡切除修补术联合奥美拉唑治疗。分析两组的治疗效果及不良反应发生情况。结果观察组与对照组总有效率经统计学分析,差异无统计学意义(P>0.05)。两组Hp阴性率经统计学分析,差异有统计学意义(P<0.05)。随访1～2年,两组复发率经统计学分析,差异无统计学意义(P>0.05)。结论采用胃溃疡切除修补术联合抗幽门螺杆菌治疗,术后Hp清除率显著高于采用胃大部分切除术治疗,使用方便,值得临床推广应用。

Objective To study the clinical effect of gastric ulcer resection suture joint drugs in treatment of gastric ulcer perforation. Methods Sixty-eight cases of gastric ulcer patients with perforation were randomly divided into the control group and the observation group. The control group used most of the stomach resection treatment, and the observation group used the repair of gastric ulcer resection combined prilosec treatment. The treatment effect and adverse reactions of the two groups were analyzed. Results The difference of total effectiveness of two groups was not statistically significant （P 〉 0.05）. The difference of Hp negative rate of two groups was statistically significant （P 〈 0.05）. Follow-up 1 to 2 years, the difference of the recurrence rate of two groups was not statistically significant （P 〉 0.05）. Conclusion The gastric ulcer resection suture unite against helicobacter pylori treatment, postoperative Hp clearance by most significantly higher than the stomach for treatment, and the recurrence rate is low, easy to use, and worth to application at clinical.