黄连软化与切制工艺优选

Optimization of Softening and Cutting Process for Coptis chinensis

目的:优化黄连的软化与切制工艺。方法:以盐酸表小檗碱、盐酸黄连碱、盐酸巴马汀和盐酸小檗碱含量为指标,采用单因素试验和正交试验优选黄连的软化和切制工艺,HPLC测定指标成分含量。结果:黄连的最佳软化方法为淋法,一般在室温下,每100 kg药材用60 L水软化48 h。黄连的最佳切制工艺为切成1～2 mm的顶头片。结论:优选的软化和切制工艺切实可行,可推广使用。

Objective： To optimize softening and cutting technology of Coptis chinensis. Method： With the content of epiberberine, coptisine, palmatine and berberine as indexes, which were determined by HPLC, softening and cutting technology of C. chinensis was optimized by single-factor test and orthogonal test. Result： Spraying was the best softening method, C. chinensis was sprayed in 48 h with 60 L water per 100 kg at room temperature medicinal herbs. Optimum cutting technology was： cutted C. chinensis into 1-2 mm piece. Conclusion： These optimized process were feasible, and could be promoted in industrial production.