鱼腥草治疗单纯疱疹病毒性角膜炎

Ordate Houttuynia as Treatment Method for Herpes Simplex Keratitis (HSK)

目的评价鱼腥草治疗单纯疱疹病毒性角膜炎(HSK)的临床效果。方法治疗组60例67眼HSK患者用阿昔洛韦滴眼液联合鱼腥草滴眼液滴眼,静脉滴注阿昔洛韦注射液和鱼腥草注射液并观察临床效果,对照组38例43眼HSK患者单用阿昔洛韦滴眼液滴眼及静脉滴注阿昔洛韦注射液,比较两组的治愈率、有效率、疗程及复发率。结果治疗组治愈59眼,占88.06%,有效6眼,占8.96%,无效2眼(深层型),占2.99%,治疗天数平均19天,随访1年,54眼中复发5眼,复发率9.26%;对照组治愈25眼,占58.14%,有效12眼,占27.91%,无效6眼,占13.95%,治疗平均天数31天,随访1年,23眼复发7眼,复发率30.43%;两组比较,治疗组疗效和疗程均优于对照组(P<0.01),治愈患者随访1年,治疗组复发率比对照组明显低。结论应用鱼腥草治疗单纯疱疹病毒性角膜炎能提高疗效,缩短病程,降低复发率。

Objective To evaluate the clinical effect of ordate houttuynia as the therapy of riSK. Method For the treatment group, 60 patients with 67 eyes suffering HSK were designed to use ordate houttuynia eye drops together with acyclovir eye drops, simultaneously intravenously dripping injecta and ordate houttuynia injecta. For the contrast group, 38 patients with 43 eyes suffering HSK were designed to just utilize acyclovir eye drops and injecta. Compare the cure rate, effective rate, course of treatment and recurrence rate in the two groups. Result For the treatment group, in 19 average treatment days, 59 eyes were cured （88.06%）, and the drugs were effective in 6 eyes （8.96%） and useless in 2 eyes （2.99%, which were sick profoundly）. During the one year follow- up, 5 ones were relapsed in 54 eyes, with the recurrence rate of 9.26%; For the contrast group, in 31 average treatment days, 25 eyes were cured （58.14%）, and the drugs were effective in 12 eyes （27.91%） and useless in 6 eyes （13.95%）. During the one year follow-up, 7 ones were relapsed in 23 eyes, with the recurrence rate of 30.43%. Make a comparison between the two groups, both the therapeutic efficiency and course were better in the treatment group than the contrast group （P〈0.01）, and during the one year follow-up with cured people, the treatment group was with obvious lower recurrence rate than the contrast group. Conclusion The use ofordate houttuynia as treatment of riSK can improve therapeutic efficiency, shorten the duration, and reduce recurrence rate.