老年高血压患者超敏C反应蛋白及尿酸与颈动脉斑块相关性研究

Relationship between the level of high sensitivity C reactive protein and serum uric acid in elderly patients with carotid atherosclerosis and hypertension

目的比较老年高血压患者颈动脉粥样硬化程度与血清超敏C反应蛋白(hs-CRP)、血尿酸(UA)水平的相关性。方法将183例老年高血压患者按B超结果分为内膜正常组、内膜增厚组、斑块形成组,比较各组间hs-CRP、UA变化。结果颈动脉内膜中层厚度(IMT)增厚组UA为(324.4±97.5)mmol/L、IMT斑块形成组UA为(330.1±97.4)mmol/L,与IMT正常组比较明显升高(P<0.05)。IMT增厚组hs-CRP异常率为47.1%,IMT斑块形成组异常率为51.5%,比IMT正常组明显升高(P<0.05)。结论老年高血压患者颈动脉粥样硬化程度与hs-CRP和血清尿酸水平密切相关。

Objective To research the relationship between high sensitivity C reactive protein（hs-CRP） and uric acid（UA） in elderly patients with carotid atherosclerosis and hypertension.Methods 183 people were divided into three groups according to the level of carotid atherosclerosis.The serum hs-CRP,and UA were measured.Results hs-CRP and UA were different in those three groups（P〈0.05）,which were higher in the carotid with plaque shaping and intimae tricking than normal.Conclusion hs-CRP and UA are related with carotid atherosclerosis in the elderly. 更多