摘要
目的观察小剂量米索前列醇-耦合剂凝胶用于足月妊娠促宫颈成熟的效果及安全性。方法足月妊娠具备引产指征的产妇122例纳入研究,试验组62例,对照组60例,前者采用米索前列醇-耦合剂凝胶对比后者米索前列醇阴道后穹隆给药促宫颈成熟。结果试验组足月妊娠促宫颈成熟的总有效率为83.9%,显著高于对照组的65.0%(P<0.05),剖宫产率亦低于对照组(P<0.05),但新生儿出生体质量及新生儿窒息率与对照组比较差异无统计学意义(P>0.05)。结论小剂量阴道后穹窿米索前列醇-耦合剂凝胶用于足月妊娠促宫颈成熟是一种安全有效的方法,对母儿无明显不良影响。
Objective To explore the efficiency of low dose misoprostol-coupling medium gel in promoting cervical ripening.Methods 122 cases of full term pregnancy with indications for labor induction were randomly assigned to 2 groups.62 women were randomized to receive Misoprostol-coupling medium gel（experimental group） and 60 women were randomized to receive misoprostol（control group） in posterior vaginal foruix.Results The total effective rates of the experimental group in promoting cervical ripening（83.9%） was better（P〈0.05） than it in control group（65.0%）,in addition with a lower caesarean section rate（P〈0.05）,meanwhile,the neonatal asphyxia rates and birth weights of two group were similar（P〉0.05）.Conclusion Low dose misoprostol-coupling medium gel can be used in promoting cervical ripening and induced labor safely and effectively,furthermore no maternal and fetus damages are produed.
出处
《检验医学与临床》
CAS
2012年第17期2161-2161,2163,共2页
Laboratory Medicine and Clinic
