养血清脑颗粒联合倍他司汀治疗椎—基底动脉供血不足眩晕的临床观察

Clinical observation of Yangxue Qingnao granule combined with betahistine in the treatment of vertebral-basilar artery insufficiency(VBI)vertigo

目的观察养血清脑颗粒联合倍他司汀治疗椎—基底动脉供血不足(VBI)眩晕的临床疗效。方法将140例VBI眩晕患者随机分治疗组和对照组各70例。对照组单纯予以倍他司汀静脉滴注治疗;治疗组在对照组治疗基础上加用养血清脑颗粒口服治疗。比较2组临床疗效,治疗前、后椎—基底动脉平均血流速度,并观察药物不良反应。结果 2组总有效率比较差异无统计学意义(P>0.05)。治疗组痊愈率和显效率分别为22.86%、47.14%,高于对照组的11.43%、31.43%;2组治疗后椎—基底动脉平均血流速度高于治疗前,且治疗组高于对照组,差异均有统计学意义(P<0.05)。2组均未发生不良反应。结论养血清脑颗粒联合倍他司汀治疗VBI眩晕疗效显著。

Objective To investigate the clinical curative effect of Yangxue Qingnao granule combined with betahistine in the treatment of vertebral-basilar artery insufficiency vertigo. Methods 140 cases of patients with VBI vertigo were di- vided into treatment group and control group, each of 70 cases. The control group received drip treatment with betahistine, while the treatment group was added with Yangxue Qingnao granule bases on the control group. Compared the clinical effect, mean flow velocity of vertebral-basilar artery before and after treatment of 2 groups, and observe the drug adverse reaction of 2 groups. Results There was no significant difference of the total effective rate between 2 groups （ P 〉 0.05 ）. The recovery rate and effective rate of treatment group were 22.86% and 47.14% ,which were higher than the control group of 11.43% and 31.43 % ;the mean flow velocity of vertebral-basilar artery of 2 groups after treatment was higher than that of before treatment, and the treatment group was higher than that of the control group, and the differences were statistically significant （ P 〈 0.05 ）. No adverse reactions were observed in both groups. Conclusion It is effective to treat VBI vertigo with Yangxue Qingnao gran- ule combined with betahistine.