早期干预对脑卒中后抑郁患者功能康复的影响

Effect of early intervention in post-stroke depression on functional rehabilitation

目的探讨早期干预治疗对脑卒中后抑郁患者的影响。方法 60例急性脑卒中后抑郁患者随机分2组,治疗组30例,予以口服抗抑郁药物及心理疏导治疗;对照组30例未进行抗抑郁治疗及心理疏导。2组均采用神经内科常规药物治疗及康复训练。采用汉密顿抑郁量表(HAMD)修订的Barthel指数(MBI)和神经功能缺损评分(NFDS)对2组治疗前和治疗后6周进行评分,对结果进行分析。结果治疗组和对照组相比,HAMD和NFDS明显降低,差异均有统计学意义(P<0.05)。MBI指数量表评分明显升高,差异有统计学意义(P<0.05)。结论早期抗抑郁治疗可以改善卒中后抑郁患者的抑郁状态,同时促进其躯体功能康复,提高日常生活质量。

Objective To discuss the impact of intervention therapy on the patients with post-stroke depression. Methods Sixty cases of acute PSD patients were randomly divided into two groups. Thirty patients were treated with oral antidepressant drugs as well as psychological counseling, and the remaining 30 patients were consulted as the blank control group. The two groups were provided with the routine treatment in the neurology department as well as rehabilitation training. Patients in the two groups were evaluated by MBI, HAMD and NFDS on the pre- and post-treatment after 6 weeks. Results Compared with control group, HAMD and NFDS scores were significantly lower and the difference was significant, and MBI was significantly higher, there was a significant statistical difference in treatment group. Conclusion The early antidepressant treatment can im- prove depressive status of the patient with post-stroke depression, facilitate physical rehabilitation and improve the quality of daily life.