重型颅脑损伤并发中枢性低钠血症48例临床分析

Heavy Craniocerebral Injury with Central Hyponatremia 48 Cases Clinical Analysis

目的探讨重型颅脑损伤患者并发中枢性低钠血症的诊断及治疗方法。方法回顾性分析48例颅脑外伤后低钠血症患者的临床资料。结果抗利尿激素异常分泌综合征（SIADH）29例，脑性耗盐综合征（CSWS）19例，治疗后，42例患者血钠恢复正常，6例患者因原发性脑损伤过重死亡。结论及早发现，正确诊治是改善重型颅脑损伤并发中枢性低钠血症患者预后的关键。

Objective To explore the diagnostic and treatment methods on severe craniocerebral injury patients with central hyponatremia. Methods 48 patients＇ clinical data were retrospective analyzed. Results 29 patients were syndrome of inappropriate antidiuretic hormone secretion （SIADH）, while another 19 patients were cerebral salt wasting syndrome （CSWS）, after appropriate treatment, 42 patients＇ sodium were recovered nomnally, but 6 patients died of severe primary brain injury .Conclusions Early detection, proper diagnosis and treatment is the key factors to improve the prognosis of patients with severe craniocerebral injury patients with central hyponatremia.