中医分阶段治疗慢性胃炎幽门螺杆菌阳性患者的疗效观察

Efficacy of Different-stage Chinese Traditional Medicine Treatment on H.pylori Positive Patients with Chronic Gastritis

目的:观察中医分阶段治疗慢性胃炎幽门螺杆菌阳性患者的疗效。方法:选择我院2011年3月-2012年3月92例确诊的幽门螺杆菌阳性的慢性胃炎患者,随机分为两组,观察组46例患者采用中医分阶段治疗,对照组46例患者采用西医治疗,所有患者均治疗3个月,观察两组HP转阴率及疗效。结果:观察组痊愈8例,显效24例,有效12例,总有效率为95.65%;对照组痊愈5例,显效11例,有效17例,总有效率71.74%;两组比较差异具有显著性,有统计学意义P<0.05。观察组HP转阴31例,占67.39%,对照组HP转阴65.22%,两组比较差异无显著性,无统计学意义P>0.05,结果证明中药在根除HP方面具有与抗菌药物相同的作用。结论:中医分阶段治疗慢性胃炎幽门螺杆菌阳性疗效显著,标本兼治,可在临床推广应用。

Objective： to observe the efficacy of different-stage Chinese traditional medicine treatment on H. pylori positive patients with chronic gastritis. Methods： from Mar. 2011 to Mar. 2012, 92 confirmed H. pylori positive patients with chronic gastritis were randomized into the observation group （n=46）,which received different-stage Chinese traditional medicine treatment, and the control group（n=46）, which received western medicine treatment. After 3 months of treatment, HP negative conversion rate and efficacy were compared between the two groups. Results： of the observation group, 8 were cured, 24 were significantly improved and 12 were moderately improved, with a total effective rate of 95.65%; of the control group, 5 were cured, 11 were significantly improved and 17 were moderately improved, with a total effective rate of 71.74%. There was statistical difference between the two groups （P〈0.05）. The negative conversion rate was 67.39% in the observation group （31/46） and 65.22% in the control group （30/46）; there was no statistical difference between the two groups （P〉0.05）. The results suggested that traditional Chinese medicine and antimicrobials are equally effective in the treatment of HP. Conclusion： different-stage traditional Chinese medicine is significantly effective in the treatment of H. pylori Positive Patients with Chronic Gastritis, being worthy of further promotion.