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低剂量人绒毛膜促性腺激素在控制性超促排卵中的应用

Effect of Low-dose Human Chorionic Gonadotropin in Controlled Ovarian Hyperstimulation
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摘要 人绒毛膜促性腺激素(hCG)与黄体生成素(LH)有着相似的化学结构,并作用于相同的受体。但因其对受体的亲和力强、半衰期长,因此效果更为持久。hCG常规用于诱发排卵与保胎用药,本文对低剂量的hCG在控制性超促排卵(COH)中的应用作一综述。 Human chorionic gonadotropin（hCG） and luteinizing hormone（LH） have the similar chemical structure.And both of them bind to the same receptor.However,hCG is more potent than LH due to its higher receptor binding affinity and a longer circulatory half-life.hCG is routinely applied in induced ovulation and maintenance of the pregnancy.This article reviewed the effect of low-dose hCG in controlled ovarian hyperstimulation（COH）.
作者 李晶洁 梁晓燕
机构地区 中山大学附属第六医院生殖中心
出处 《生殖与避孕》 CAS CSCD 2012年第9期615-617,共3页 Reproduction and Contraception
关键词 人绒毛膜促性腺激素(hCG) 控制性超促排卵(COH) 低剂量 human chorionic gonadotropin （hCG） controlled ovarian hyperstimulation （COH） low dose
分类号 R714.8 [医药卫生—妇产科学]
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参考文献12

  • 1Pierce JG, Parsons TF. Glycoprotein hormones: structure and function. Annu Rev Biochem, 1981, 50:465-95.
  • 2Rahman NA, Rao C V. Recent progress in luteinizing hormone/ human chorionic gonadotrophin hormone research. Mol Hum Reprod, 2009, 15(11):703-11.
  • 3Rao C V. Differential properties of human chorionic gonadot- rophin and human luteinizing hormone binding to plasma membranes of bovine corpora lutea. Acta Endocrinol (Copenh), 1979, 90(4):696-710.
  • 4Propst AM, Hill MJ, Bates GW, et al. Low-dose human chorionic gonadotropin may improve in vitro fertilization cycle outcomes in patients with low luteinizing hormone levels after gonadotropin-releasing hormone antagonist administration. Fertil Steril, 2011, 96(4):898-904.
  • 5Koichi K, Yukiko N, Shima K, et al. Efficacy of low-dose human chorionic gonadotropin (hCG) in a GnRH antagonist protocol. J Assist Reprod Genet, 2006, 23(5):223-8.
  • 6Serafini P, Yadid I, Motta EL, et al. Ovarian stimulation with daily late follicular phase administration of low-dose human chori0nic gonadotropin for in vitro fertilization: a prospective, randomized trial. Fertil Steril, 2006, 86(4):830-8.
  • 7Filicori M, Cognigni GE, Gamberini E, et al. Efficacy of low- dose human chorionic gonadotropin alone to complete con- trolled ovarian stimulation. Fertil Steril, 2005, 84(2):394- 401.
  • 8Gomes MK, Vieira CS, Moura M D, et al. Controlled ovarian stimulation with exclusive FSH followed by stimulation with hCG alone, FSH alone or hMG. Eur J Obstet Gynecol Reprod Biol, 2007, 130(1):99-106.
  • 9Beretsos P, Partsinevelos G A, Arabatzi E, et al. "hCG priming" effect in controlled ovarian stimulation through a long protocot. Reprod Biol Endocrinol, 2009, 7:91.
  • 10Drakakis P, Loutradis D, Beloukas A, et al. Early hCG addition to rFSH for ovarian stimulation in IVF provides better results and the cDNA copies of the hCG receptor may be an indicator of successful stimulation. Reprod Biol Endocrinol, 2009, 7:110.

二级参考文献7

  • 1Filicorl M,Cognigni GE,Taraborrelli S,et 81. Low-dose human chorionic gonadotropin therapy can improve sensitivity to exogenous follicle-stimulating hormone in patients with secondary amenorrhea [ J ]. Fertil Stefil, 1999,72 (6) : 1118-1120.
  • 2Filicori M ,Cognigni GE ,Samara A ,et al. The use of LH activity to drive folliculogenesis :exploring uncharted territories in ovulation induction [ J ]. Hum Reprod Update, 2002,8 (6) : 543-557.
  • 3于传鑫,李儒芝.妇科内分泌治疗学[M].上海:复旦大学出版社.2009:454-509.
  • 4Filicofi M ,Fazleabas AT,Huhtaniemi I,et al. Move1 concepts of human ehorionic gonadotropin:reproductive system interactions and potential in the management of infertility [J]. Fertit Steril, 2005,84 (2) : 275-284.
  • 5Drakakis P, Lutrasdis D, Beloukas A, et al. Early hCG addition to rFSH for ovarian stimulation in IVF provides better results and the eDNA copies of the hCG receptor may be an indicator of successful stimulation [J ]. Reprod Biomed Online,2009,7 (1) :110-119.
  • 6陈新娜,乔杰,李红真,王颖,李蓉,王丽娜.19例下丘脑性闭经的诊断及助孕治疗分析[J].生殖与避孕,2009,29(6):402-405. 被引量：9
  • 7孟昱时,马兰,杨晓玲.低促性腺激素性腺功能减退症的临床特征和助孕治疗分析[J].实用妇产科杂志,2011,27(3):217-218. 被引量：19

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生殖与避孕
2012年 第9期

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