G—CSF诱发健康外周血造血干细胞捐献者血液肿瘤的风险
被引量:1
摘要
目前,重组人粒细胞集落刺激因子(rhG-CSF)作为动员剂已常规用于健康人外周血造血干/祖细胞采集,但rhG-CSF用于临床治疗而诱发急性髓系白血病(AML)和骨髓增生异常综合征(MDS)不断见诸报道,由此引发了对健康供者使用rhG-CSF的担忧。现就健康人使用rhG-CSF后细胞遗传学、免疫学改变及可能诱发AML的风险作一综述。
出处
《国际输血及血液学杂志》
CAS
2012年第5期459-462,共4页
International Journal of Blood Transfusion and Hematology
参考文献30
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