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双黄连冻干粉合丹参粉针治疗湿热瘀结型慢性盆腔炎临床研究 被引量:2

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摘要 目的观察双黄连冻干粉合丹参粉针治疗湿热瘀结型慢性盆腔炎的临床疗效。方法将60例湿热瘀结型慢性盆腔炎患者随机数字表法分为对照组和治疗组各30例,对照组用双黄连冻干粉静滴,治疗组予双黄连冻干粉+丹参粉针静注,2组均治疗14 d。观察2组患者临床疗效和治疗前后血清肿瘤坏死因子-a(TNF-a)、白介素-2(IL-2)浓度的变化。结果治疗组和对照组总有效率分别为96.7%和63.3%,2组比较差异有显著性(P<0.05)。治疗组治疗后血清IL-2较治疗前上升,血清TNF-a较治疗前下降(均P<0.05),上述指标与对照组治疗后比较差异亦有显著性差异(P<0.05)。结论双黄连冻干粉联合丹参粉针可影响炎症介质,提高湿热瘀结型慢性盆腔炎患者免疫功能,减轻炎症。
作者 郑慧颖 陈哲
机构地区 漳州市中医院
出处 《福建中医药》 2012年第4期17-18,共2页 Fujian Journal of Traditional Chinese Medicine
基金 福建省卫生厅资助课题(WZY0923)
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  • 1Aukrust P, Ueland T, Lien E, et al. Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy[J]. Americal Journal of cardiology, 1999,83: 376 ~ 382
  • 2Jacqueline Parkin, Bryony Cohen. An overview of the immune system. The Lancet, 2001,357: 1777 ~ 1789
  • 3金伯泉主编.细胞与分子免疫学.第二版.北京:科学出版社,2001.149
  • 4Herrera- Garza EH, Stetson SJ, Cubillos- Garzon A,et al. Tumor necrosis factor-α:a mediator of disease progression in the failing human heart[J]. Chest, 1999,115:1170~1174
  • 5Atkins MB.Interleukin-2:clinical applications.Semin Oncol,2002;29(Suppl 7):12-17
  • 6Kovacs JA,Vogel S,Albert JM,et al.Controlled trial of intcrleukin-2 infusions in patients infected with the human immunodeficiency virus.N Engl J Med,1996;335:1350-1356
  • 7Rosenberg SA,Yang JC,Topalian SL,et al.Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2.JAMA,1994;271:907-913
  • 8Sereti I,Anthony KB,Martinez-Wilson H,et al.IL-2 induced CD4+ T-cell expansion in HIV infected patients is associated with long-term decreases in T-cell proliferation.Blood,2004;104:775-780
  • 9Malek TR,Bayer AL.Tolerance,not immunity,crucially depends on IL-2.Nat Rev Immunol,2004;4:665-674
  • 10Cohney SJ,Sanden D,Cacalano NA,et al.SOCS-3 Is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation.Mol Cell Biol,1999,19:4980-4988

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