胸腺上皮肿瘤的多层螺旋CT表现与其病理学分型的对照研究

Multi-slice CT finding of thymic epithelial tumors and its correlation with WHO histopathologic classification

目的:探讨胸腺上皮肿瘤多层螺旋CT(MSCT)影像特征与其WHO组织病理学分型间的相关性。方法:回顾性分析44例经手术病理证实的胸腺上皮肿瘤患者的术前MSCT表现,并将其按WHO组织病理学分型的简化型分组进行对比。结果:胸腺上皮肿瘤的MSCT侵袭性征象包括轮廓不规则、肿瘤-心脏-大血管接触面(MCI)呈灌注型、纵隔脂肪线消失及瘤-肺界面毛刺影,这些特征在高危胸腺瘤及胸腺癌中均较低危胸腺瘤中更常见(P均<0.05),而肿瘤周围淋巴结肿大在胸腺癌中出现频率较低危胸腺瘤及高危胸腺瘤高(P均<0.05)。结论:MSCT能够反映胸腺上皮肿瘤的生物学特性,具有预测其组织学类型的潜力。

Objective To study the nmhi-slice CT （MSCT） finding of thymic epithelial tumors （TET）and its correla- tion with the WHO histopathologic classification. Methods The MSCT findings of 44 cases of TET proved surgically and pathologically were reviewed and correlated to the WHO histopathologie classification. Patients were subgrouped based on the WHO classification scheme： low-risk thymomas, high-risk thymomas and thynfie carcinomas. Results Signs of invasive growth including irregular contour, mass-cardiovascular interface （MCI） with cast type, disappearance of fat line around tu- mor, and mass-lung interface with spicule sign were significantly more frequent in the high-risk thymomas and thymic car- cinomas than that in the low-risk thymomas （P〈0.05）. Lymph node enlargement around the tumor was seen more frequently in thymic carcinomas than in low-risk thymomas and high-risk thymomas （P〈0.05）. Conclusions MSCT finding can reflect the biologic behavior of TET, and has good correlation with the WHO histopathologie classification.