苏州地区健康体检人群幽门螺杆菌感染情况调查研究

The study on information of Helicobacter pylori infection in healthy people in Suzhou

目的了解苏州地区健康体检人群幽门螺杆菌(Hp)感染现状,并就性别、年龄、职业等感染相关因素进行分析。方法随机抽取2010年8至2011年9月来苏州市立医院体检的健康人群9 285例作为研究对象,年龄从20～80岁,采用胶体金法检测血清幽门螺杆菌尿素酶抗体。结果苏州地区体检人群Hp感染率为38.3%,男性与女性之间感染率差异有统计学意义(P<0.05)。不同年龄组之间的感染率差异有统计学意义(P<0.05),年龄在21～30岁的体检者,其Hp的感染率较低,为30.1%;年龄在41～70岁,感染率达高峰,且趋于稳定,其中41～50、51～60、61～70岁三个年龄段之间的体检者,感染率分别为42.6%、41.7%、42.7%。不同职业者之间的Hp感染率差异有统计学意义(P<0.05),医务人员的感染率最低(34.3%),其次是教师的感染率也较低(36.4%),司机和记者的Hp感染率较高,分别为41.8%、43.9%。结论苏州地区体检人群Hp感染低于全国水平,其感染与性别、年龄、职业因素均相关。

Objective To understand the information of helicobacter pylori（Hp） infection in healthy people in Suzhou,and to analyzes the factors of sex,age,occupation which related to Hp infections. Methods 9 285 cases aging from 20-80 years old were chosen randomly from healthy people in August 2010 to September 2011. The helicobacter pylori antibody were detected using Hp Urease Immunogold Testing Kits. Results The Hp infection rates was 38.3% in Suzhou healthy people,There was significant difference between men and women（P^0.05）. There exist significant differences among different age groups about the infection rates. At the age of 21 to 30 years old,the Hp infection rate was the lowest（30. 1%）; However, at the age of 41- 70 years old, the infection rate was higher than other ages, and tended steadily. Including three ages of 41- 50 years old, 51- 60 years old, 61- 70 years old, their in- fection rates were respectively 42.6 %, 41. 7/0/0 and 42.7 %. There exist significant differences in different occupations on the Hp infection rates. The infection rate of medical staffs was the lowest among all the healthy people（34.3 %%0）. The second lower rate was the teacher group （36.4%）. The Hp infection rates were higher in the driver group and the reporter group,respectively 41.8% and 43.9%. Conclusion The Hp infection level is lower in SuZhou area than the national rate, the factors of Hp infection is associated with sex, age, occupation.