子宫肌瘤不同治法的比较研究

Comperative Study on the Different Treatments of Uterine Fibroids

目的观察不同方法治疗子宫肌瘤的疗效。方法将我院门诊及住院收治的77例患者按照临床研究的随机、对照原则,并结合患者自身情况,分别给予米非司酮药物(药物组)、子宫动脉栓塞术组(手术1组)和腹腔镜子宫肌瘤剔除术(手术2组),观察疗效及随访生活质量。结果与药物组比较,手术1、2组有效率均较高,差异有统计学意义(P<0.05);手术2组优于手术1组,差异有统计学意义(P<0.05)。随访6个月发现,药物组在躯体功能、整体健康状况得分上低于手术1、2组,但在情感功能得分则优于手术1、2组,差异均有统计学意义(P<0.05)。结论腹腔镜子宫肌瘤剔除术、子宫动脉栓塞术成功率好,但米非司酮对于患者预后情感功能上改善明显,这可能与手术对于患者心理造成的影响有关。

Objective To explore the Clinical comparison of different methods for the treatment of uterine fibroids. Methods The 77 patients admitted to our hospital patients according to clinical studies, randomized, control principle, and with the patient＇s own condition, were given mifepristone treatment group, operation treatment of uterine artery embolization group and laparoscopic myomeetomy observe the curative effect and the follow - up of quality of life. Results Operation opera- tion was successful in all 2 groups, and the drug group, 2 groups of 1, operation etiieieney is high, the difference was statisti- cally significant （ P 〈 O. 05 ） ; operation 2 group was better than the operation of 1 groups, the difference was statistically signifi- cant （ P 〈 0. 05 ）. Follow up of 6 months found, drug group in somatic function, overall health status score lower than 1, 2 sets of operation, but in emotional function score better than the operation 1, 2 groups, differences were statistically significant （ P 〈 0. 05 ）. Conclusion Laparoseopie myomectomy for uterine artery embolization, success rate, but the prognosis of the patients with mifepristone for emotional function improved significantly, which may be related to operation for patients with psychological impact on.