单分散介孔纳米载体合成及表征

Synthesis and Characterization of Monodisperse Mesoporous Silica Nanocarrier

通过Stber法制备粒径约100 nm的SiO2纳米粒子,并以非离子表面活性剂嵌段共聚物为模板剂在纳米粒子表面再合成介孔SiO2层。在磷酸盐诱导剂的作用下可使核/壳结构的纳米粒子快速沉淀出来。再通过煅烧除去表面活性剂获得粒径均匀的球形介孔纳米载体。通过动态光散射(DLS)、扫描电镜(SEM)、透射电镜(TEM)、X射线衍射(XRD)、比表面积测定(BET)和氮气吸附脱附测定等技术对材料进行表征。纳米载体的平均有效粒径约为183 nm,介孔孔道为5.5 nm,具有良好的分散性(PDI:0.076),比表面积高达158.6 m2/g,孔容积0.22 cm3/g。结果表明,该法可以简单快速地制备纳米载体。

On SiO2 nanoparticles of about 100 nm prepared by Stsber method, additional layer of SiO2 was formed using non-ionic surfactant block copolymcrs as template agent. The core/shell nanoparticles could be precipitated out from the solution in the presence of phosphate inducer. Furthermore the template was removed by calcination to obtain the spherical mesoporous nanocarriers with uniform size. The nanocarrier was characterized by dynamic light scattering （DLS）, scanning electron microscopy （SEM）, transmis- sion electron microscopy （TEM）, X-ray diffraction （XRD）, specific surface area measurements （BET）, and nitrogen adsorption and desorption. The average effective size of nanocarriers is about 183 nm with 5.5 nm pore size and a good dispersion（ PDI ：0. 076）. The specific surface area is as high as 158.6 m2/g and the pore volume is 0.22 cm3/g. These suggest this is a facile method to prepare nano-carriers simply and rapidly.