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益生菌联合美沙拉嗪治疗溃疡性结肠炎疗效观察 被引量:4

Clinical efficacy of combining probiotic with mesalazine in the treatment of ulcerative colitis
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摘要 目的探讨益生菌联合美沙拉嗪治疗溃疡性结肠炎临床疗效。方法选取2009年11月~2011年10月治疗UC患者70例,随机分为观察组与对照组,评价2组治疗效果。结果观察组经治疗后总有效率91.4%,对照组总有效率71.4%,2组患者经治疗后总有效率及复发情况差异具有统计学意义。结论益生菌联合美沙拉嗪可以改善溃疡性结肠炎症状,且复发率较低,值得临床推广。 Objective To investigate the clinical efficacy of probiotics combined with mesalazine in the treatment of ulcerative colitis. Methods 70 patients were randomly divided into observation group and control group, evaluation the treatment effect of 2 groups. Results The total effective rate and relapse were statistically significant. Conclusion The probiotic combined with mesalazine can improve the symptoms of ulcerative colitis, with a lower relapse rate.
作者 符小兼
出处 《中国卫生产业》 2012年第20期17-17,共1页 China Health Industry
关键词 益生菌 美沙拉嗪 溃疡性结肠炎 Probiotic Mesalazine Ulcerative colitis
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  • 1白爱平,欧阳钦.益生菌治疗炎症性肠病的机制[J].胃肠病学,2005,10(4):240-242. 被引量:33
  • 2IritChermesh,RamiEliakim.Probiotics and the gastrointestinal tract:Where are we in 2005?[J].World Journal of Gastroenterology,2006,12(6):853-857. 被引量:10
  • 3欧阳钦,Rakesh Tandon,KL Goh,潘国宗,KM Fock,Claudio Fiocchi,SK Lam,萧树东,张虎,梁红亮,王玉芳.亚太地区炎症性肠病处理共识意见(一)[J].胃肠病学,2006,11(4):233-238. 被引量:123
  • 4Paolo Gionchetti,Fernando Rizzello,Karen M Lammers,Claudia Morselli,Lucia Sollazzi,Samuel Davies,Rosy Tambasco,Carlo Calabrese,Massimo Campieri.Antibiotics and probiotics in treatment of inflammatory bowel disease[J].World Journal of Gastroenterology,2006,12(21):3306-3313. 被引量:12
  • 5张静,韩英,王继恒.炎症性肠病与肠道细菌研究进展[J].世界华人消化杂志,2007,15(12):1406-1410. 被引量:29
  • 6Dotan I.Rachmilewitz D.probiotics in inflammatory bowel diseasepossible mechanisms of action[J].Curr opin Gastroenterol,2005,21(4):426.
  • 7Satrtor RB.Therapeutic manipulation of enteric microflora in inflammatory and inflammatory bowel disease antibiotics,probiotics and prebiotics[J].Gastroenterology,2004,126:1620.
  • 8Ishikawa H,Akedo I,Umesaki Y,et al.Randomized controlled trial of the effect of bifidobateria fermented mile on ulcerative colitis[J].J Am coll Nutr,2003,22(1):56.
  • 9Zocco MA.dalverme LZ.Cremonini F,et al.Efficacy of Lacrobacilhis GC inmaintaining remission of ulcerative colitis[J].Aliment pharamacol Ther,2006,23(1):1567.
  • 10Pena JA,Versatovic J.Lactobacillus rhamnosus GC decrease TNF alpha production in lipopolysacharide-activated nurine maerophages by a contact-independent mechanism[J].Cell Microb iol,2003,5(4):277.

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  • 1刘建生,田怡,张晓红,刘进,马铭,袁耀宗,林健.溃疡性结肠炎时一氧化氮和超氧化物歧化酶变化及益生菌对其影响机制[J].中国医师进修杂志(内科版),2007,30(6):20-22. 被引量:7
  • 2袁超,陈星星,喻群力.美沙拉嗪联合培菲康治疗溃疡性结肠炎的研究[J].现代医药卫生,2007,23(17):2565-2566. 被引量:8
  • 3WANG YF, OUYANG Q, APDW 2004 Chinese IBD Working Group. Ulcerative colitis in China: retrospective analysis of 3100 hospitalized patients [J]. J Gastroenterol Hepatol, 2007, 22 (9) : 1450-1455.
  • 4SHU SM, XU B, WANG X, et al. The biodiversity and composition of the dominant fecal microbiota in patients with inflammatory bowel disease [J]. Diagn Microbiol Infect Dis, 2013, 75 (3): 245-251.
  • 5Gentschew L, Ferguson LR. Role of nutrition and microbiota in susceptibility to inflammatory bowel diseases[ J ]. Mol N utr Food Res, 2012, 56 (4): 524-535.
  • 6Ahme S, Hagslatt ML. Effect of lactobacilli on paracellular permeability in the gut[J]. Nutrients, 2011, 3 (1) : 104-117.
  • 7Mallon P, Mckay D, Kirk S, et al. Probiotics for induction of remission in ulcerative colitis [J]. Cochrane Database of Systematic Reviews, 2007 (4).
  • 8ZHU Y, TANG RK, ZHAO P, et al. Can oral 5-aminosalicylic acid be administered once daily in the treatment of mild-to-moderate ulcerative coliris? A recta-analysis of randomized-controlled trials [J]. EurJ Gastroenterol Hepatol, 2012, 24. (5) : 487-494.
  • 9Ford AC, Khan KJ, Achkar J. Efficacy of oral vs. topical, or combined oral and topical 5-Aminosalicylates, in ulcerative colitis: systematic review and Meta-Analysis [J]. American Journal of Gastroenterology, 2012, 107 (2): 167-176.
  • 10A. G. R?seth,M. K. Fagerhol,E. Aadland,H. Schj?nsby.Assessment of the Neutrophil Dominating Protein Calprotectin in Feces: A Methodologic Study[J].Scandinavian Journal of Gastroenterology.1992(9)

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